PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15498778-4	2004	While searching for a DNA-PK-independent end-joining activity, we found that the pretreatment of DNA-PK-proficient and -deficient rodent cells with an inhibitor of the poly(ADP-ribose) polymerase-1 enzyme (PARP-1) led to increased cytotoxicity of the highly efficient DNA double-strand breaking compound calicheamicin gamma1.	calicheamicin gamma(1)I	304-324	poly(ADP-ribose) polymerase 1	Homo sapiens	168-204	
15498778-4	2004	While searching for a DNA-PK-independent end-joining activity, we found that the pretreatment of DNA-PK-proficient and -deficient rodent cells with an inhibitor of the poly(ADP-ribose) polymerase-1 enzyme (PARP-1) led to increased cytotoxicity of the highly efficient DNA double-strand breaking compound calicheamicin gamma1.	calicheamicin gamma(1)I	304-324	poly(ADP-ribose) polymerase 1	Homo sapiens	206-212	
15498778-5	2004	In addition, the repair kinetics of the DSBs induced by calicheamicin gamma1 was delayed both in PARP-1-proficient cells pretreated with the PARP-1 inhibitor and in PARP-1-deficient cells.	calicheamicin gamma(1)I	56-76	poly(ADP-ribose) polymerase 1	Homo sapiens	97-103	
15498778-5	2004	In addition, the repair kinetics of the DSBs induced by calicheamicin gamma1 was delayed both in PARP-1-proficient cells pretreated with the PARP-1 inhibitor and in PARP-1-deficient cells.	calicheamicin gamma(1)I	56-76	poly(ADP-ribose) polymerase 1	Homo sapiens	141-147	
15498778-5	2004	In addition, the repair kinetics of the DSBs induced by calicheamicin gamma1 was delayed both in PARP-1-proficient cells pretreated with the PARP-1 inhibitor and in PARP-1-deficient cells.	calicheamicin gamma(1)I	56-76	poly(ADP-ribose) polymerase 1	Homo sapiens	141-147	
2109651-2	1990	Calicheamicin gamma 1 caused an increase in poly(ADP-ribose) polymerase activity in HL-60 cells parallel to cell death.	calicheamicin gamma(1)I	0-21	poly(ADP-ribose) polymerase 1	Homo sapiens	44-71