PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23469846-5	2013	We found that while suppression of Pin1, either by using its inhibitor Juglone or a shRNA plasmid against Pin1, induces tau hyperphosphorylation and GSK-3beta activation both in vivo and in vitro, inhibition of GSK-3beta by SB216763 or LiCl reverses tau hyperphosphorylation.	juglone	71-78	glycogen synthase kinase 3 beta	Homo sapiens	149-158	
30013652-0	2018	Juglone suppresses epithelial-mesenchymal transition in prostate cancer cells via the protein kinase B/glycogen synthase kinase-3beta/Snail signaling pathway.	juglone	0-7	glycogen synthase kinase 3 beta	Homo sapiens	103-133	
30013652-8	2018	Furthermore, juglone prevented inactivation of glycogen synthase kinase-3beta (GSK-3beta), an endogenous inhibitor of Snail in a dose-dependent manner.	juglone	13-20	glycogen synthase kinase 3 beta	Homo sapiens	47-77	
30013652-8	2018	Furthermore, juglone prevented inactivation of glycogen synthase kinase-3beta (GSK-3beta), an endogenous inhibitor of Snail in a dose-dependent manner.	juglone	13-20	glycogen synthase kinase 3 beta	Homo sapiens	79-88	
30013652-9	2018	Lithium chloride (LiCl), a GSK-3beta inhibitor, prevented juglone-mediated downregulation of Snail expression and upregulation of E-cadherin.	juglone	58-65	glycogen synthase kinase 3 beta	Homo sapiens	27-36	
30013652-11	2018	Inhibition of the phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/Akt pathway by LY294002 augmented juglone-mediated GSK-3beta activity by inhibiting Ser9 phosphorylation.	juglone	106-113	glycogen synthase kinase 3 beta	Homo sapiens	123-132	
30013652-12	2018	These findings indicated that juglone suppresses EMT via the Akt/GSK-3beta/Snail pathway, consequently decreasing the invasiveness of PC cells.	juglone	30-37	glycogen synthase kinase 3 beta	Homo sapiens	65-74