PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17578901-11 2007 Inhibition of renal uptake (via OAT3) and efflux processes (via MRP2 and MRP4) explains the possible sites of drug-drug interaction for methotrexate with probenecid and some NSAIDs, including their glucuronides. Probenecid 154-164 ATP binding cassette subfamily C member 4 Homo sapiens 73-77 11856762-7 2002 Both probenecid and dipyridamole are potent MRP4 inhibitors. Probenecid 5-15 ATP binding cassette subfamily C member 4 Homo sapiens 44-48 33307708-5 2021 Our data indicates that 4-Cl-KYN crosses the blood-brain barrier via the amino acid transporter LAT1 (SLC7A5) after which the 7-Cl-KYNA metabolite leaves the brain extracellular fluid via probenecid-sensitive organic anion transporters OAT1/3 (SLC22A6 and SLC22A8) and MRP4 (ABCC4). Probenecid 188-198 ATP binding cassette subfamily C member 4 Homo sapiens 269-273 33307708-5 2021 Our data indicates that 4-Cl-KYN crosses the blood-brain barrier via the amino acid transporter LAT1 (SLC7A5) after which the 7-Cl-KYNA metabolite leaves the brain extracellular fluid via probenecid-sensitive organic anion transporters OAT1/3 (SLC22A6 and SLC22A8) and MRP4 (ABCC4). Probenecid 188-198 ATP binding cassette subfamily C member 4 Homo sapiens 275-280 22155354-7 2012 We have now found that decreased MRP4 expression induced by a short hairpin RNA (shRNA), or chemical inhibition with probenecid, increased (+)-anti-trans-B[a]PDE-dGuo formation in cells treated with (-)-B[a]P-7,8-dihydrodiol, but not the ultimate carcinogen (+)-anti-trans-B[a]PDE. Probenecid 117-127 ATP binding cassette subfamily C member 4 Homo sapiens 33-37 23385799-7 2013 Inhibition of MRP4 in HTM cells by MK571 or probenecid resulted in cell shape changes and decreases in actin stress fibers and MLC phosphorylation. Probenecid 44-54 ATP binding cassette subfamily C member 4 Homo sapiens 14-18 15504935-8 2004 Probenecid stimulated MRP2 at low concentrations but had no effect on MRP4; but at high probenecid concentrations, both MRP2 and MRP4 were inhibited. Probenecid 0-10 ATP binding cassette subfamily C member 4 Homo sapiens 129-133 15357833-7 2004 Transport was further inhibited by probenecid, an inhibitor of endogenous non-selective transporters as well as of MRP4/5 and by cycloheximide as an inhibitor of de novo protein synthesis. Probenecid 35-45 ATP binding cassette subfamily C member 4 Homo sapiens 115-121