PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26774050-4 2016 We found that AQP4 KO mice exhibited increased basal and inducible canonical NF-kappaB activity, and showed significantly enhanced gliosis (astrocytosis and microgliosis) in chronic MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)/probenecid PD models, companying with the increase in the production of IL-1beta and TNF-alpha in the midbrain. Probenecid 234-244 aquaporin 4 Mus musculus 14-18 24317635-0 2014 Probenecid protects against transient focal cerebral ischemic injury by inhibiting HMGB1 release and attenuating AQP4 expression in mice. Probenecid 0-10 aquaporin 4 Mus musculus 113-117 24317635-11 2014 Moreover, AQP4 protein expression was downregulated in the cortical penumbra following post-stroke treatment with probenecid. Probenecid 114-124 aquaporin 4 Mus musculus 10-14