PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25931146-3	2015	In the human hepatocarcinoma cell line HepG2, cytotoxic response to GCDCA was characterized by the reduced activity of the respiratory complexes II+III, the increased expression and activation of the transcription factor Sp1, and a higher binding capacity of this at positions -1386, -632 and -104 of the NOS-3 promoter (pNOS-3).	Glycochenodeoxycholic Acid	68-73	nitric oxide synthase 3	Homo sapiens	305-310	
27490694-2	2016	We have previously reported that glycochenodeoxycholic acid (GCDCA) down-regulates gene expression by increasing SP1 binding to the NOS-3 promoter in an oxidative stress dependent manner.	Glycochenodeoxycholic Acid	33-59	nitric oxide synthase 3	Homo sapiens	132-137	
27490694-2	2016	We have previously reported that glycochenodeoxycholic acid (GCDCA) down-regulates gene expression by increasing SP1 binding to the NOS-3 promoter in an oxidative stress dependent manner.	Glycochenodeoxycholic Acid	61-66	nitric oxide synthase 3	Homo sapiens	132-137	
20020783-5	2009	GCDCA reduced the intracellular Ca(2+) concentration and NOS-3 expression and enhanced cell death in HepG2.	Glycochenodeoxycholic Acid	0-5	nitric oxide synthase 3	Homo sapiens	57-62	
19837105-7	2010	GCDCA reduced intracellular Ca2+ concentration and NOS-3 expression, and enhanced cell death in HepG2.	Glycochenodeoxycholic Acid	0-5	nitric oxide synthase 3	Homo sapiens	51-56