PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17940890-5 2008 The effect of 25 ng/ml FGF2 was blocked by 10 microM genistein, a tyrosine kinase inhibitor and by 25 microM LY294002, a PI3 kinase inhibitor. Genistein 53-62 fibroblast growth factor 2 Rattus norvegicus 23-27 8864900-3 1996 Stimulation of [3H]thymidine incorporation (TDR) into DNA by bFGF was determined in the presence of phorbol myristate acetate of (PMA) to down-regulate the protein kinase C (PKC) pathway, genistein, an inhibitor of tyrosine kinase and H-7, a PKC inhibitor, bFGF 10(-8) M and PMA 10(-7) M increased TDR by 242 and 245%, respectively. Genistein 188-197 fibroblast growth factor 2 Rattus norvegicus 61-65 11707523-8 2001 By contrast, genistein, an inhibitor of tyrosine kinases, blocked the effects of bFGF and EGF without affecting the effect of IGF-1. Genistein 13-22 fibroblast growth factor 2 Rattus norvegicus 81-85 9838095-3 1998 Genistein, a protein tyrosine kinase inhibitor, significantly attenuated the effect of bFGF. Genistein 0-9 fibroblast growth factor 2 Rattus norvegicus 87-91 9023013-6 1996 The protein tyrosine kinase inhibitor, 0.5 mM genistein, inhibited arachidonic acid release in basic fibroblast growth factor-stimulated acini, whereas 100 microM vanadate, a protein tyrosine phosphatase inhibitor, enhanced arachidonic acid release. Genistein 46-55 fibroblast growth factor 2 Rattus norvegicus 95-125 8831488-5 1996 Genistein blocked the effects of FGF-2. Genistein 0-9 fibroblast growth factor 2 Rattus norvegicus 33-38 8864900-6 1996 Genistein at 10 micrograms/ml blocked the mitogenic effect of bFGF and partially inhibited the mitogenic effect of PMA. Genistein 0-9 fibroblast growth factor 2 Rattus norvegicus 62-66 8864900-7 1996 Genistein at 100 micrograms/ml also blocked both bFGF- and PMA-induced increases in c-fos mRNA. Genistein 0-9 fibroblast growth factor 2 Rattus norvegicus 49-53 7815474-7 1994 The bFGF-induced increases in barium currents are dependent on tyrosine phosphorylation, since the effects of bFGF are blocked by genistein, a tyrosine kinase inhibitor. Genistein 130-139 fibroblast growth factor 2 Rattus norvegicus 4-8 7815474-7 1994 The bFGF-induced increases in barium currents are dependent on tyrosine phosphorylation, since the effects of bFGF are blocked by genistein, a tyrosine kinase inhibitor. Genistein 130-139 fibroblast growth factor 2 Rattus norvegicus 110-114 1480180-10 1992 Furthermore, treatment of follicles with EGF or bFGF inhibited the spontaneous initiation of apoptosis, and the suppressive effects of these growth factors were also attenuated by co-treatment with genistein. Genistein 198-207 fibroblast growth factor 2 Rattus norvegicus 48-52