PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7829625-2 1995 Interaction of TSH with the human FSH receptor (hFSH-R) is a possible pathophysiological mechanism for this syndrome that has not been explored due to the lack of hFSH-free TSH preparations and the scarcity of a suitable hFSH-R-based assay system. Thyrotropin 15-18 follicle stimulating hormone receptor Homo sapiens 34-46 17356048-14 2007 CONCLUSIONS: Pediatric gonadal hyperstimulation associated with severe primary hypothyroidism is likely due to the actions of the elevated concentrations of TSH on the wild-type hFSHR, and this response is not dependent upon the hFSHR isoform. Thyrotropin 157-160 follicle stimulating hormone receptor Homo sapiens 178-183 17356048-14 2007 CONCLUSIONS: Pediatric gonadal hyperstimulation associated with severe primary hypothyroidism is likely due to the actions of the elevated concentrations of TSH on the wild-type hFSHR, and this response is not dependent upon the hFSHR isoform. Thyrotropin 157-160 follicle stimulating hormone receptor Homo sapiens 229-234 15080154-7 2004 Similar to D567N, the T449A FSHr mutant shows an increase of its sensitivity to both hCG and TSH, together with an increase in basal activity. Thyrotropin 93-96 follicle stimulating hormone receptor Homo sapiens 28-32 15001619-7 2004 Similar to D567N, the T449A FSHr mutant shows an increase of its sensitivity to both hCG and TSH, together with an increase in basal activity. Thyrotropin 93-96 follicle stimulating hormone receptor Homo sapiens 28-32 25495063-6 2015 Our experience suggests that patients" carrier of a mutation of FSHr gene are at risk of ovarian pathologies also when non-pregnant and in the presence of low TSH levels. Thyrotropin 159-162 follicle stimulating hormone receptor Homo sapiens 64-68 20378412-4 2010 In most FSHR mutations, a hypersensitivity to human chorionic gonadotrophin (HCG) or thyroid-stimulating hormone (TSH) is described. Thyrotropin 85-112 follicle stimulating hormone receptor Homo sapiens 8-12 20378412-4 2010 In most FSHR mutations, a hypersensitivity to human chorionic gonadotrophin (HCG) or thyroid-stimulating hormone (TSH) is described. Thyrotropin 114-117 follicle stimulating hormone receptor Homo sapiens 8-12 20378412-10 2010 This report confirms for the first time the in-vitro findings in a single clinical case that TSH as well as HCG leads to spontaneous OHSS in patients with FSHR D567N mutation. Thyrotropin 93-96 follicle stimulating hormone receptor Homo sapiens 155-159 19499413-3 2009 It may also depend on activating mutations of the FSH receptor (FSHR) gene that cause ovarian hyper-responsiveness to circulating FSH or even cross-responsiveness of FSHR to hormones having a structure similar to FSH, such as hCG or TSH. Thyrotropin 233-236 follicle stimulating hormone receptor Homo sapiens 50-62 19499413-3 2009 It may also depend on activating mutations of the FSH receptor (FSHR) gene that cause ovarian hyper-responsiveness to circulating FSH or even cross-responsiveness of FSHR to hormones having a structure similar to FSH, such as hCG or TSH. Thyrotropin 233-236 follicle stimulating hormone receptor Homo sapiens 64-68 17721928-8 2008 Contrary to the mutations described previously, the p.Ser128Tyr FSHR mutant displayed increase in affinity and sensitivity toward hCG and did not show any constitutive activity, nor promiscuous activation by TSH. Thyrotropin 208-211 follicle stimulating hormone receptor Homo sapiens 64-68 17937064-11 2007 CONCLUSIONS: The elevated TSH in these patients and prior demonstration of the in vitro ability of TSH to bind to the FSH receptor lead us to hypothesize that the gonadal stimulation in these patients is TSH-mediated. Thyrotropin 99-102 follicle stimulating hormone receptor Homo sapiens 118-130 10665997-1 2000 Since cross-reactivity of TSH with the human FSH receptor has been reported, in this study we tested the effect of thyroid-stimulating antibody (TSAb) and thyroid stimulation-blocking antibody (TSBAb) on Chinese hamster ovary cells expressing human FSH receptor (CHO-hFSH-R cells). Thyrotropin 26-29 follicle stimulating hormone receptor Homo sapiens 45-57 7829625-2 1995 Interaction of TSH with the human FSH receptor (hFSH-R) is a possible pathophysiological mechanism for this syndrome that has not been explored due to the lack of hFSH-free TSH preparations and the scarcity of a suitable hFSH-R-based assay system. Thyrotropin 15-18 follicle stimulating hormone receptor Homo sapiens 48-54 7829625-2 1995 Interaction of TSH with the human FSH receptor (hFSH-R) is a possible pathophysiological mechanism for this syndrome that has not been explored due to the lack of hFSH-free TSH preparations and the scarcity of a suitable hFSH-R-based assay system. Thyrotropin 15-18 follicle stimulating hormone receptor Homo sapiens 221-227 7525632-1 1994 Recently we identified a unique region, residues 9-30 in the extracellular domain of the FSH receptor, capable of binding FSH but not LH or TSH. Thyrotropin 140-143 follicle stimulating hormone receptor Homo sapiens 89-101