PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25921843-9 2015 Compared to baseline, metformin significantly improved metabolic parameters and insulin sensitivity, increased SIRT1 gene/protein expression and SIRT1 promoter chromatin accessibility, elevated mTOR gene expression with concomitant reduction in p70S6K phosphorylation in subjects" PBMCs, and modified the plasma N-glycan profile. n-glycan 312-320 ribosomal protein S6 kinase B1 Homo sapiens 245-251