PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30503610-1 2019 beta2-microglobulin (B2M), a component of major histocompatibility complex class I, plays an important role in host immune reaction to tumor, and inactivation of B2M is known to contribute to resistance to immune checkpoint blockade (ICB) treatment. indole-2-carboxylic acid 234-237 beta-2-microglobulin Homo sapiens 0-19 30503610-1 2019 beta2-microglobulin (B2M), a component of major histocompatibility complex class I, plays an important role in host immune reaction to tumor, and inactivation of B2M is known to contribute to resistance to immune checkpoint blockade (ICB) treatment. indole-2-carboxylic acid 234-237 beta-2-microglobulin Homo sapiens 21-24 30503610-1 2019 beta2-microglobulin (B2M), a component of major histocompatibility complex class I, plays an important role in host immune reaction to tumor, and inactivation of B2M is known to contribute to resistance to immune checkpoint blockade (ICB) treatment. indole-2-carboxylic acid 234-237 beta-2-microglobulin Homo sapiens 162-165 30503610-4 2019 Of note, bi-allelic B2M alterations, which had been known to be accumulated during ICB treatment, were frequently found (3/9) in ICB treatment-naive CRCs. indole-2-carboxylic acid 83-86 beta-2-microglobulin Homo sapiens 20-23 30503610-4 2019 Of note, bi-allelic B2M alterations, which had been known to be accumulated during ICB treatment, were frequently found (3/9) in ICB treatment-naive CRCs. indole-2-carboxylic acid 129-132 beta-2-microglobulin Homo sapiens 20-23 30503610-7 2019 Our results show that B2M mutation is common in MSU CRCs, which is one of the main targets for ICB treatment, suggesting that frequent B2M mutation status should be reminded for MSU CRCs in patient selection of ICB. indole-2-carboxylic acid 95-98 beta-2-microglobulin Homo sapiens 22-25 30503610-7 2019 Our results show that B2M mutation is common in MSU CRCs, which is one of the main targets for ICB treatment, suggesting that frequent B2M mutation status should be reminded for MSU CRCs in patient selection of ICB. indole-2-carboxylic acid 211-214 beta-2-microglobulin Homo sapiens 22-25