PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20003456-2 2009 We wished to explore the possibility that a carbocation intermediate is formed during the cleavage reaction of BCMO1, as is seen for many isoprenoid biosynthesis enzymes, and to determine which residues in the substrate binding cleft are necessary for catalytic and substrate binding activity. Terpenes 138-148 beta-carotene oxygenase 1 Mus musculus 111-116