PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2949310-3 1987 A situation analogous to the latent stage of human hepatic porphyria can be produced in chick embryos by injecting an inhibitor of ferrochelatase (the last enzyme in the heme biosynthesis pathway); the simultaneous injection of a porphyrinogenic drug (e.g. barbiturate) results in a strong increase of liver porphyrin levels, as is found in human hepatic porphyrias. barbituric acid 257-268 ferrochelatase Gallus gallus 131-145