PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17896178-1 2008 Cytosolic serine hydroxymethyltransferase (cSHMT) is key to intersection of folate-metabolic pathway, participating in the pyrimidine synthesis for DNA repair. pyrimidine 123-133 serine hydroxymethyltransferase 1 Homo sapiens 0-41 27530298-1 2016 The cytosolic and mitochondrial isoforms of serine hydroxymethyltransferase (SHMT1 and SHMT2, respectively) are well-recognized targets of cancer research, since their activity is critical for purine and pyrimidine biosynthesis and because of their prominent role in the metabolic reprogramming of cancer cells. pyrimidine 204-214 serine hydroxymethyltransferase 1 Homo sapiens 77-82 17896178-1 2008 Cytosolic serine hydroxymethyltransferase (cSHMT) is key to intersection of folate-metabolic pathway, participating in the pyrimidine synthesis for DNA repair. pyrimidine 123-133 serine hydroxymethyltransferase 1 Homo sapiens 43-48 33326752-5 2021 We show that silencing SHMT1 in cells with low RFC expression impairs pyrimidine biosynthesis and tumor growth in vivo. pyrimidine 70-80 serine hydroxymethyltransferase 1 Homo sapiens 23-28