PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8806785-3 1996 When NADPH is used as electron donor with a reconstituted system composed of d-OR and P450c17, the addition of t-OR, flavodoxin, or cytochrome c inhibited the rate of formation of 17 alpha-hydroxyprogesterone. NADP 5-10 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 86-93 9257124-2 1997 NADPH (300 microM) causes a 3.6-fold stimulation of malondialdehyde formation (thiobarbituric acid-reactive substances) and a 29% cytochrome P450c17 loss within 1 h at 37 degrees C, but has no effect on lipid peroxidation in the presence of the iron chelator desferrioxamine. NADP 0-5 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 141-148 17505056-1 2007 P450 oxidoreductase (POR) has a pivotal role in facilitating electron transfer from nicotinamide adenine dinucleotide phosphate to microsomal cytochrome P450 (CYP) enzymes, including the steroidogenic enzymes CYP17A1 and CYP21A2. NADP 84-127 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 209-216 8504753-9 1993 To catalyze its activities, P450c17 must receive electrons from NADPH via a flavoprotein termed P450 reductase. NADP 64-69 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 28-35 27426448-0 2016 Cytochrome b5 Activates the 17,20-Lyase Activity of Human Cytochrome P450 17A1 by Increasing the Coupling of NADPH Consumption to Androgen Production. NADP 109-114 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 58-78 30921671-1 2019 Cytochrome P450 17A1 (CYP17A1; EC: 1.14.14.19) is a critically important bifunctional enzyme with nicotinamide adenine dinucleotide phosphate (NADPH) as its cofactor that catalyzes the formation of all endogenous androgens. NADP 98-141 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 0-20 30921671-1 2019 Cytochrome P450 17A1 (CYP17A1; EC: 1.14.14.19) is a critically important bifunctional enzyme with nicotinamide adenine dinucleotide phosphate (NADPH) as its cofactor that catalyzes the formation of all endogenous androgens. NADP 98-141 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 22-29 30921671-1 2019 Cytochrome P450 17A1 (CYP17A1; EC: 1.14.14.19) is a critically important bifunctional enzyme with nicotinamide adenine dinucleotide phosphate (NADPH) as its cofactor that catalyzes the formation of all endogenous androgens. NADP 143-148 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 0-20 30921671-1 2019 Cytochrome P450 17A1 (CYP17A1; EC: 1.14.14.19) is a critically important bifunctional enzyme with nicotinamide adenine dinucleotide phosphate (NADPH) as its cofactor that catalyzes the formation of all endogenous androgens. NADP 143-148 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 22-29 21070833-1 2011 P450 oxidoreductase (POR) transports electrons from NADPH to all microsomal cytochrome P450 enzymes, including steroidogenic P450c17, P450c21 and P450aro. NADP 52-57 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 125-132 15220035-5 2004 METHODS: We did sequence analysis of the human gene encoding P450 oxidoreductase, an enzyme that is important in electron transfer from NADPH to P450C17 and P450C21. NADP 136-141 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 145-152