PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7588400-2 1995 11 beta-HSD1 (the hepatic isoform) was reversible and NADP(H)-dependent. NADP 54-61 11-beta-hydroxysteroid dehydrogenase 1 Ovis aries 0-12 9178432-3 1997 The liver-type, NADP(+)-dependent 11 beta-HSD-1, has an affinity in the micromolar range and bidirectional activity. NADP 16-23 11-beta-hydroxysteroid dehydrogenase 1 Ovis aries 34-47 9178432-10 1997 The NADP(+)-dependent activity had a Km for corticosterone of 4 +/- 1.3 nM for a Km for cortisol of 35.2 +/- 2 nM, 100-fold lower than that described for the 11 beta-HSD-1 in the liver of sheep and other species, and was more prevalent in the microsomes than the nuclei. NADP 4-11 11-beta-hydroxysteroid dehydrogenase 1 Ovis aries 158-171