PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29567975-2 2018 In the mitochondria, IDH2 also plays a key role in protecting mitochondrial components from oxidative stress by supplying NADPH to both glutathione reductase (GSR) and thioredoxin reductase 2 (TXNRD2). NADP 122-127 gutter shaped root Mus musculus 159-162 28658624-2 2017 NADPH-dependent reduction of thioredoxin-1 (Trx1) disulfide and glutathione disulfide by thioredoxin reductase-1 (TrxR1) and glutathione reductase (Gsr), respectively, fuels antioxidant systems and deoxyribonucleotide synthesis. NADP 0-5 gutter shaped root Mus musculus 148-151 28658624-3 2017 Mouse livers lacking both TrxR1 and Gsr sustain these essential activities using an NADPH-independent methionine-consuming pathway; however, it remains unclear how this reducing power is distributed. NADP 84-89 gutter shaped root Mus musculus 36-39