PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1986928-2 1991 One of the major lesions was characterized as a loss of steroid-17 alpha-hydroxylase activity, a key step in the biosynthetic pathway leading to active corticosteroid hormones. corticosteroid hormones 152-175 steroid 17-alpha-hydroxylase/17,20 lyase Bos taurus 56-84