PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22792179-0 2012 Lipocalin prostaglandin D synthase and PPARgamma2 coordinate to regulate carbohydrate and lipid metabolism in vivo. Carbohydrates 73-85 peroxisome proliferator activated receptor gamma Mus musculus 39-49 22792179-9 2012 Overall, L-PGDS and PPARgamma2 coordinate to regulate carbohydrate and lipid metabolism. Carbohydrates 54-66 peroxisome proliferator activated receptor gamma Mus musculus 20-30 21143167-7 2011 PPARgamma plays an important role in regulating carbohydrate and lipid metabolism, and ligands for PPARgamma can improve insulin sensitivity and reduce triglyceride levels. Carbohydrates 48-60 peroxisome proliferator activated receptor gamma Mus musculus 0-9 21143167-7 2011 PPARgamma plays an important role in regulating carbohydrate and lipid metabolism, and ligands for PPARgamma can improve insulin sensitivity and reduce triglyceride levels. Carbohydrates 48-60 peroxisome proliferator activated receptor gamma Mus musculus 99-108 29414316-9 2018 SIGNIFICANCE: In current study, for the first time, PPARgamma agonism by rosiglitazone was proved to promote thermogenesis under near-freezing conditions and enhance the heat generating response against cold-induced hypothermia in mice by switching the fuel preference from carbohydrates to lipids. Carbohydrates 274-287 peroxisome proliferator activated receptor gamma Mus musculus 52-61 17003330-6 2006 In mouse, coexistence of the P465L PPARgamma mutation and the leptin-deficient state creates a mismatch between insufficient adipose tissue expandability and excessive energy availability, unmasking the deleterious effects of PPARgamma mutations on carbohydrate metabolism and replicating the characteristic clinical symptoms observed in human patients with dominant-negative PPARgamma mutations. Carbohydrates 249-261 peroxisome proliferator activated receptor gamma Mus musculus 35-44 15919792-8 2005 These findings suggest that PPARgamma2 is required for the maintenance of normal insulin sensitivity in mice but also raises the intriguing notion that PPARgamma2 may be necessary for the adverse effects of a high-fat diet on carbohydrate metabolism. Carbohydrates 226-238 peroxisome proliferator activated receptor gamma Mus musculus 28-38 15919792-8 2005 These findings suggest that PPARgamma2 is required for the maintenance of normal insulin sensitivity in mice but also raises the intriguing notion that PPARgamma2 may be necessary for the adverse effects of a high-fat diet on carbohydrate metabolism. Carbohydrates 226-238 peroxisome proliferator activated receptor gamma Mus musculus 152-162 34303773-8 2021 Results indicated that obesity and DEHP synergistically regulated carbohydrate uptake, lipolysis, and abnormality of adipose tissue, via the upstream regulators Pparg, Lipe, Cd44, and Irs1. Carbohydrates 66-78 peroxisome proliferator activated receptor gamma Mus musculus 161-166 33596122-3 2021 Peroxisome-proliferator activated receptors (PPARs), in particular PPARdelta and PPARgamma, are involved in the regulation of lipids and carbohydrates and, along adenosine-monophosphate (AMP)-activated protein kinase (AMPK) and protein kinase B (Akt/PKB), are implicated in translocation of glucose transporter 4 (GLUT4). Carbohydrates 137-150 peroxisome proliferator activated receptor gamma Mus musculus 81-90 24893713-8 2014 Results indicate that PPARgamma signaling increased resulting in enhanced cycling of lipid and carbohydrate substrates into glycolytic/gluconeogenic pathways favoring energy production versus storage in 2,4-DNT-exposed WT and PPARalpha (-/-) mice. Carbohydrates 95-107 peroxisome proliferator activated receptor gamma Mus musculus 22-31 27540527-2 2016 Although PPARgamma acts as a master transcription factor in adipocyte differentiation, it is also associated with a variety of cell functions including carbohydrate and lipid metabolism, glucose homeostasis, cell proliferation and cell differentiation. Carbohydrates 152-164 peroxisome proliferator activated receptor gamma Mus musculus 9-18 25051434-8 2014 In summary, transgenic overexpression of PPARgamma in beta-cells in diet-induced obesity negatively impacts whole-animal carbohydrate metabolism associated with altered islet lipid content, increased expression of beta-oxidative genes, and reduced beta-cell mass. Carbohydrates 121-133 peroxisome proliferator activated receptor gamma Mus musculus 41-50