PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8016100-3 1994 When these mutations were introduced into a strain with reduced oligosaccharyltransferase activity (due to the wbp1-1 mutation), a severe growth defect was observed: accumulation of suboptimal lipid-linked oligosaccharide and reduced oligosaccharyltransferase activity resulted in a severe underglycosylation of secreted proteins. lipid-linked oligosaccharides 193-221 dolichyl-diphosphooligosaccharide-protein glycotransferase Saccharomyces cerevisiae S288C 111-117