PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6428117-5 1984 In the presence of 3-isobutyl-1-methylxanthine, the TSH response to either of the peptides was augmented, and the difference in the maximal TSH release by either peptide became insignificant, suggesting that TRH as well as DN-1417 act through the same mechanism of mediation by the cyclic nucleotides. 1-Methyl-3-isobutylxanthine 19-46 thyrotropin releasing hormone Rattus norvegicus 208-211