PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3108877-3 1987 The synthetic diacylglycerols 1,2-dioctanoylglycerol (diC8) and 1-oleoyl-2-acetylglycerol strongly enhanced IFN-beta 2, but not IFN-beta 1, gene expression in human fibroblasts (FS-4 strain). 1,2-dioctanoylglycerol 30-52 interleukin 6 Homo sapiens 108-118 3108877-3 1987 The synthetic diacylglycerols 1,2-dioctanoylglycerol (diC8) and 1-oleoyl-2-acetylglycerol strongly enhanced IFN-beta 2, but not IFN-beta 1, gene expression in human fibroblasts (FS-4 strain). 1,2-dioctanoylglycerol 54-58 interleukin 6 Homo sapiens 108-118 3108877-7 1987 diC8 was found to protect FS-4 cells from the cytopathic effect of vesicular stomatitis virus; this protection was blocked by polyclonal or monoclonal antibodies that neutralize IFN-beta, suggesting that the antiviral effect was due to the secretion of IFN-beta 2 by the diC8-treated fibroblasts. 1,2-dioctanoylglycerol 0-4 interleukin 6 Homo sapiens 253-263 3108877-8 1987 The calcium ionophore A23187 (1-10 microM) also elicited an increase in the level of IFN-beta 2 mRNA in FS-4 fibroblasts; appropriate combinations of A23187 and diC8 had at least an additive effect in enhancing IFN-beta 2 mRNA levels. 1,2-dioctanoylglycerol 161-165 interleukin 6 Homo sapiens 85-95 3108877-8 1987 The calcium ionophore A23187 (1-10 microM) also elicited an increase in the level of IFN-beta 2 mRNA in FS-4 fibroblasts; appropriate combinations of A23187 and diC8 had at least an additive effect in enhancing IFN-beta 2 mRNA levels. 1,2-dioctanoylglycerol 161-165 interleukin 6 Homo sapiens 211-221