PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2361470-1 1990 Activators of protein kinase C, such as phorbol myristate acetate (PMA) and the synthetic diacylglycerol dioctanoylglycerol (diC8), either stimulate or inhibit PTH release depending on the extracellular Ca2+ concentration. 1,2-dioctanoylglycerol 125-129 parathyroid hormone Bos taurus 160-163 2361470-12 1990 With respect to secretion, either of the protein kinase C agonists (i.e. PMA or diC8) or the Ca2+ ionophore ionomycin inhibited PTH release at 0.5 mM Ca2+. 1,2-dioctanoylglycerol 80-84 parathyroid hormone Bos taurus 128-131 2536321-8 1989 At 2.0 mM extracellular Ca2+, PMA (10(-6) M) bryostatin-1 (10(-7) M), and 1,2-dioctanoylglycerol (3 x 10(-4) M) blunted the suppressive effects of high Ca2+ on secretion, thus stimulating PTH release 252 +/- 45%, 122 +/- 20%, and 485 +/- 95% over control levels, respectively. 1,2-dioctanoylglycerol 74-96 parathyroid hormone Bos taurus 188-191