PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8476056-4	1993	Both CCK-8 and gastrin increased inositol phosphates, with CCK-8 (1 microM) and gastrin (3 microM) causing a 40- and 14-fold increase in [3H]IP1, 10- and 6-fold for [3H]IP2, and 8- and 4-fold for [3H]IP3.	Inositol 1,4,5-Trisphosphate	200-203	gastrin	Homo sapiens	15-22	
8476056-4	1993	Both CCK-8 and gastrin increased inositol phosphates, with CCK-8 (1 microM) and gastrin (3 microM) causing a 40- and 14-fold increase in [3H]IP1, 10- and 6-fold for [3H]IP2, and 8- and 4-fold for [3H]IP3.	Inositol 1,4,5-Trisphosphate	200-203	gastrin	Homo sapiens	80-87	
3304752-5	1987	When gastrin binds to its receptor on the parietal cell, phosphatidylinositol biphosphate (IP2) in the plasma membrane is converted to inositol 1,4,5-triphosphate (IP3), which acts as the secondary intracellular messenger to increase intracellular calcium and initiate the process that eventually leads to acid secretion.	Inositol 1,4,5-Trisphosphate	135-162	gastrin	Homo sapiens	5-12	
2026251-0	1991	Biphasic kinetics of inositol 1,4,5-trisphosphate accumulation in gastrin-stimulated parietal cells.	Inositol 1,4,5-Trisphosphate	21-49	gastrin	Homo sapiens	66-73	
2026251-7	1991	We concluded that: (i) gastrin induced a rapid increase in Ins(1,4,5)P3 content via a mechanism insensitive to PTx and to extracellular Ca2+, and (ii) gastrin induced a sustained increase in Ins(1,4,5)P3 level via a mechanism sensitive to PTx and to extracellular Ca2+.	Inositol 1,4,5-Trisphosphate	59-71	gastrin	Homo sapiens	23-30	
2026251-7	1991	We concluded that: (i) gastrin induced a rapid increase in Ins(1,4,5)P3 content via a mechanism insensitive to PTx and to extracellular Ca2+, and (ii) gastrin induced a sustained increase in Ins(1,4,5)P3 level via a mechanism sensitive to PTx and to extracellular Ca2+.	Inositol 1,4,5-Trisphosphate	59-71	gastrin	Homo sapiens	151-158	
2026251-7	1991	We concluded that: (i) gastrin induced a rapid increase in Ins(1,4,5)P3 content via a mechanism insensitive to PTx and to extracellular Ca2+, and (ii) gastrin induced a sustained increase in Ins(1,4,5)P3 level via a mechanism sensitive to PTx and to extracellular Ca2+.	Inositol 1,4,5-Trisphosphate	191-203	gastrin	Homo sapiens	23-30	
2026251-7	1991	We concluded that: (i) gastrin induced a rapid increase in Ins(1,4,5)P3 content via a mechanism insensitive to PTx and to extracellular Ca2+, and (ii) gastrin induced a sustained increase in Ins(1,4,5)P3 level via a mechanism sensitive to PTx and to extracellular Ca2+.	Inositol 1,4,5-Trisphosphate	191-203	gastrin	Homo sapiens	151-158	
3304752-5	1987	When gastrin binds to its receptor on the parietal cell, phosphatidylinositol biphosphate (IP2) in the plasma membrane is converted to inositol 1,4,5-triphosphate (IP3), which acts as the secondary intracellular messenger to increase intracellular calcium and initiate the process that eventually leads to acid secretion.	Inositol 1,4,5-Trisphosphate	164-167	gastrin	Homo sapiens	5-12	
7900813-6	1995	Gastrin caused a rise in inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] level within 5 s of stimulation.	Inositol 1,4,5-Trisphosphate	25-53	gastrin	Homo sapiens	0-7	
3741886-11	1986	13, G814-G823) we conclude that: carbachol, CCK-8, gastrin and histamine increase parietal cell [Ca2+]i initially by release of Ca2+ from the same intracellular store(s); the release of [Ca2+]i in response to carbachol and CCK-8 in both chief and parietal cells appear to be mediated by IP3; however, other mechanisms may be involved in histamine-induced release of parietal cell Ca2+.	Inositol 1,4,5-Trisphosphate	287-290	gastrin	Homo sapiens	51-58	
7900813-6	1995	Gastrin caused a rise in inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] level within 5 s of stimulation.	Inositol 1,4,5-Trisphosphate	55-67	gastrin	Homo sapiens	0-7