PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19199985-3	2009	Our first rationally designed MTDL was the polyamine caproctamine (1), which provided a synergistic cholinergic action against AD by antagonizing muscarinic M(2) autoreceptors and inhibiting acetylcholinesterase (AChE).	caproctamine	53-65	acetylcholinesterase (Cartwright blood group)	Homo sapiens	191-211	
19199985-3	2009	Our first rationally designed MTDL was the polyamine caproctamine (1), which provided a synergistic cholinergic action against AD by antagonizing muscarinic M(2) autoreceptors and inhibiting acetylcholinesterase (AChE).	caproctamine	53-65	acetylcholinesterase (Cartwright blood group)	Homo sapiens	213-217	
15588084-3	2004	In the present paper we expanded SAR studies of 3, the ethyl analogue of the AChE inhibitor caproctamine (2), by investigating the role of its octamethylene spacer separating the two amide functions through the replacement with dipiperidine and dianiline moieties.	caproctamine	92-104	acetylcholinesterase (Cartwright blood group)	Homo sapiens	77-81	
12134831-1	2002	An RP-HPLC study for the pKa determination of a series of basic compounds related to caproctamine, a dibenzylaminediamide reversible inhibitor of acetylcholinesterase, is reported.	caproctamine	85-97	acetylcholinesterase (Cartwright blood group)	Homo sapiens	146-166	
11141093-1	2001	In a search for less flexible analogues of caproctamine (1), a diamine diamide endowed with an interesting AChE affinity profile, we discovered compound 2, in which the terminal 2-methoxybenzyl groups of 1 have been incorporated into a tricyclic system.	caproctamine	43-55	acetylcholinesterase (Cartwright blood group)	Homo sapiens	107-111