PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18992858-10 2008 Because UGT2B17 encodes an enzyme catabolizing steroid hormones, we measured the concentrations of serum testosterone and estradiol for 236 young Chinese males and assessed their UGT2B17 copy number. Estradiol 122-131 UDP glucuronosyltransferase family 2 member B17 Homo sapiens 8-15 19487245-9 2009 Mutagenesis and siRNA experiments indicate that UGT2B17 expression is also regulated by 17beta-estradiol via the ERU, which is fully conserved in both promoters. Estradiol 88-104 UDP glucuronosyltransferase family 2 member B17 Homo sapiens 48-55 19487245-10 2009 Because UGT2B15 and UGT2B17 inactivate steroid hormones by glucuronidation, the regulation of their genes by 17beta-estradiol may maintain steroid hormone homeostasis and prevent excessive estrogen signaling activity. Estradiol 109-125 UDP glucuronosyltransferase family 2 member B17 Homo sapiens 20-27 18992858-11 2008 Subjects without UGT2B17 had significantly higher concentrations of testosterone and estradiol. Estradiol 85-94 UDP glucuronosyltransferase family 2 member B17 Homo sapiens 17-24 18719240-7 2008 UGT2B4 was specific for epiestradiol; UGT2B7 glucuronidated both diastereomers, with high affinity for epiestradiol, whereas UGT2B17 only glucuronidated beta-estradiol. Estradiol 153-167 UDP glucuronosyltransferase family 2 member B17 Homo sapiens 125-132 30616396-7 2018 High Atlas Moroccans and Algerians show low frequency of UGT2B17del, a variant associated with high concentrations of testosterone and oestradiol. Estradiol 135-145 UDP glucuronosyltransferase family 2 member B17 Homo sapiens 57-64