PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26165333-9 2015 Consistent with the in vitro results, the mRNA levels revealed decreased ERalpha and increased PR in in vivo treatment of E2 and 2-ME. Estradiol 122-124 progesterone receptor Rattus norvegicus 95-97 26597778-4 2016 As an antagonist, tamoxifen partially inhibited the estradiol-dependent increase in the number of PR-immunoreactive neurons and in PR mRNA and protein levels, without interfering with the subcellular location of the protein. Estradiol 52-61 progesterone receptor Rattus norvegicus 98-100 26597778-4 2016 As an antagonist, tamoxifen partially inhibited the estradiol-dependent increase in the number of PR-immunoreactive neurons and in PR mRNA and protein levels, without interfering with the subcellular location of the protein. Estradiol 52-61 progesterone receptor Rattus norvegicus 131-133 26597778-5 2016 We suggest that tamoxifen influence on PR expression in the VMNvl critically depends on the presence or absence of estradiol. Estradiol 115-124 progesterone receptor Rattus norvegicus 39-41 18208546-0 2008 Endogenous oestradiol regulates progesterone receptor expression in the brain of female rat fetuses: what is the source of oestradiol? Estradiol 11-21 progesterone receptor Rattus norvegicus 32-53 21473877-7 2011 In the GH3 cells, a large increase in PR mRNA and protein was observed in a concentration-dependent manner after parabens treatment that was effectively blocked in the presence of antagonist of 17beta-estradiol (fulvestrant). Estradiol 194-210 progesterone receptor Rattus norvegicus 38-40 22147012-0 2012 Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17beta-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesis. Estradiol 127-143 progesterone receptor Rattus norvegicus 26-47 22147012-0 2012 Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17beta-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesis. Estradiol 127-143 progesterone receptor Rattus norvegicus 96-117 22147012-0 2012 Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17beta-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesis. Estradiol 127-143 progesterone receptor Rattus norvegicus 70-73 22147012-5 2012 Pgr was hormonally responsive only in CA1 pyramidal neurons, and the induction of Pgr by E2 was partly antagonized by P4 only on the 30-d schedule. Estradiol 89-91 progesterone receptor Rattus norvegicus 82-85 17244199-2 2007 One physiological function of oestradiol is the induction of progesterone receptor (PR) expression in a variety of behaviourally relevant brain regions, including the ventromedial nucleus of the hypothalamus (VMN), the medial preoptic nucleus of the preoptic area (MPOA), the arcuate nucleus (ARC) and the medial central grey (MCG). Estradiol 30-40 progesterone receptor Rattus norvegicus 61-82 17244199-2 2007 One physiological function of oestradiol is the induction of progesterone receptor (PR) expression in a variety of behaviourally relevant brain regions, including the ventromedial nucleus of the hypothalamus (VMN), the medial preoptic nucleus of the preoptic area (MPOA), the arcuate nucleus (ARC) and the medial central grey (MCG). Estradiol 30-40 progesterone receptor Rattus norvegicus 84-86 17244199-9 2007 These results, taken together with the findings that virtually all oestradiol-induced PR containing cells in the brain express ER, suggest that these neurones represent sites of functional interaction of nuclear receptor coactivators with ovarian steroid receptors in the brain. Estradiol 67-77 progesterone receptor Rattus norvegicus 86-88 16837883-8 2006 Vaginal progesterone receptor protein was increased fivefold by estradiol and all three SERMs tested. Estradiol 64-73 progesterone receptor Rattus norvegicus 8-29 16837612-0 2006 Oestradiol-17beta inhibits tamoxifen-induced LHRH self-priming blocking hormone-dependent and ligand-independent activation of the gonadotrope progesterone receptor in the rat. Estradiol 0-17 progesterone receptor Rattus norvegicus 143-164 17003284-8 2006 Functionally, E(2)-stimulated changes in PR mRNA isoform ratios in rat, mouse or LbetaT2 cells correlated with the degree of progesterone augmentation of GnRH-stimulated LH secretion in these models. Estradiol 14-18 progesterone receptor Rattus norvegicus 41-43 16942525-12 2006 CONCLUSION: Estradiol down-regulated ERalpha and up-regulated PR expression in the vagina, suggesting this may be a mechanism to prevent continued proliferation of the epithelium by surges of estradiol during the estrous cycle. Estradiol 192-201 progesterone receptor Rattus norvegicus 62-64 16461543-2 2006 Since LC neurons are responsive to estradiol, which induces progesterone receptor (PR) expression, this study aimed to investigate whether LC neurons express the alpha-estradiol receptor (alphaER) and PR as well as comparing such responses to that observed in the preoptic area (POA). Estradiol 35-44 progesterone receptor Rattus norvegicus 60-81 16461543-2 2006 Since LC neurons are responsive to estradiol, which induces progesterone receptor (PR) expression, this study aimed to investigate whether LC neurons express the alpha-estradiol receptor (alphaER) and PR as well as comparing such responses to that observed in the preoptic area (POA). Estradiol 35-44 progesterone receptor Rattus norvegicus 83-85 17033158-6 2006 The expression of progesterone receptor mRNA in the anterior pituitary was significantly increased by either NP, OP, bisphenol A, or estradiol, but bisphenol A was less effective. Estradiol 133-142 progesterone receptor Rattus norvegicus 18-39 14967892-8 2003 In rats on P18, 17beta-estradiol injection did not change PR mRNA levels after sham-operation but induced an increase in PR mRNA levels of rats ovariectomized 6 h before the treatment. Estradiol 16-32 progesterone receptor Rattus norvegicus 121-123 16284289-6 2005 Progesterone exerted a stimulatory effect through the progesterone receptor on the induction of ROS generation processes and intracellular pathways, resulting in TGF-beta1 expression and HSC activation, and fibrogenic effects were inhibited by oestradiol. Estradiol 244-254 progesterone receptor Rattus norvegicus 54-75 16145313-9 2005 17beta-estradiol, but not the SSE, down-regulated uterine epithelial progesterone receptor (PR), compared with ovariectomized rats. Estradiol 0-16 progesterone receptor Rattus norvegicus 69-90 16145313-9 2005 17beta-estradiol, but not the SSE, down-regulated uterine epithelial progesterone receptor (PR), compared with ovariectomized rats. Estradiol 0-16 progesterone receptor Rattus norvegicus 92-94 16145313-10 2005 In the stromal compartment, progesterone receptor expression was fully up-regulated by 17beta-estradiol treatment and, to a lesser extent, by SSE treatment. Estradiol 87-103 progesterone receptor Rattus norvegicus 28-49 12385821-7 2002 In addition, E(2)-stimulated transactivation of an estrogen-response-element reporter gene as well as E(2)-induced upregulation of the PR were also inhibited by PR ligands. Estradiol 13-17 progesterone receptor Rattus norvegicus 135-137 12918018-7 2003 We observed that PR mRNA expression was increased in POA-AHA and HYP of the animals treated with estradiol or testosterone 3 hours after treatments, compared with the vehicle-treated control group. Estradiol 97-106 progesterone receptor Rattus norvegicus 17-19 12918018-8 2003 We also found a significant increase in PR mRNA and protein expression in POA-AHA and HYP on the day of VO in both estradiol and testosterone defeminized rats. Estradiol 115-124 progesterone receptor Rattus norvegicus 40-42 12798354-1 2003 In this work, we determined the expression pattern and the hormonal regulation of progesterone receptor (PR) isoforms in the rat lung of ovariectomized female rats after estradiol (E2) and progesterone (P4) treatments. Estradiol 170-179 progesterone receptor Rattus norvegicus 82-103 12798354-1 2003 In this work, we determined the expression pattern and the hormonal regulation of progesterone receptor (PR) isoforms in the rat lung of ovariectomized female rats after estradiol (E2) and progesterone (P4) treatments. Estradiol 170-179 progesterone receptor Rattus norvegicus 105-107 12457037-4 2002 Estradiol-induced PR expression in the preoptic area and the hippocampus, whereas progesterone did not modify the effect of estradiol. Estradiol 0-9 progesterone receptor Rattus norvegicus 18-20 12969244-0 2003 Changes in progesterone receptor isoforms content in the rat brain during the oestrous cycle and after oestradiol and progesterone treatments. Estradiol 103-113 progesterone receptor Rattus norvegicus 11-32 12969244-2 2003 In the hypothalamus and the preoptic area of ovariectomized rats, PR-A and PR-B content was increased by oestradiol, whereas progesterone significantly diminished the content of both PR isoforms after 3 h of treatment in the hypothalamus, but not in the preoptic area. Estradiol 105-115 progesterone receptor Rattus norvegicus 66-68 12385821-7 2002 In addition, E(2)-stimulated transactivation of an estrogen-response-element reporter gene as well as E(2)-induced upregulation of the PR were also inhibited by PR ligands. Estradiol 13-17 progesterone receptor Rattus norvegicus 161-163 12385821-7 2002 In addition, E(2)-stimulated transactivation of an estrogen-response-element reporter gene as well as E(2)-induced upregulation of the PR were also inhibited by PR ligands. Estradiol 102-106 progesterone receptor Rattus norvegicus 135-137 12385821-7 2002 In addition, E(2)-stimulated transactivation of an estrogen-response-element reporter gene as well as E(2)-induced upregulation of the PR were also inhibited by PR ligands. Estradiol 102-106 progesterone receptor Rattus norvegicus 161-163 10465261-5 1999 Treatment with estradiol (48 h) stimulated progesterone receptor (PR) messenger RNA expression and binding to [3H]R5020, a synthetic progestin. Estradiol 15-24 progesterone receptor Rattus norvegicus 43-64 12065892-6 2002 Estradiol-induced increases in the number of progesterone receptor-immunoreactive cells in the hypothalamic ventromedial nucleus and the medial preoptic area were not inhibited by this dose of ICI but were inhibited by 500 microg/day tamoxifen, an antiestrogen that can cross the blood-brain barrier. Estradiol 0-9 progesterone receptor Rattus norvegicus 45-66 10537124-3 1999 In estradiol-treated ovariectomized rats, approximately 80% of NT/neuromedin N mRNA-expressing cells in sections through the dorsomedial division of the ARC and approximately 60% of such cells in sections through the ventrolateral division of the ARC were found to contain PR mRNA. Estradiol 3-12 progesterone receptor Rattus norvegicus 273-275 10465261-5 1999 Treatment with estradiol (48 h) stimulated progesterone receptor (PR) messenger RNA expression and binding to [3H]R5020, a synthetic progestin. Estradiol 15-24 progesterone receptor Rattus norvegicus 66-68 9742655-13 1998 The androgen and progesterone receptor systems were less selective in that 17 beta-estradiol activated these systems within 3 orders of magnitude of the primary ligand. Estradiol 75-92 progesterone receptor Rattus norvegicus 17-38 10494488-4 1999 The highest PR and c-fos mRNA content was observed 3 h and 2 h after 17 beta-estradiol administration, respectively. Estradiol 72-86 progesterone receptor Rattus norvegicus 12-14 9717846-2 1998 Although 17beta-estradiol (E) can induce PR mRNA and activate PR promoter-reporter constructs in other cell types, the effects of E in granulosa cells appear to be indirect. Estradiol 9-25 progesterone receptor Rattus norvegicus 41-43 9717846-2 1998 Although 17beta-estradiol (E) can induce PR mRNA and activate PR promoter-reporter constructs in other cell types, the effects of E in granulosa cells appear to be indirect. Estradiol 9-25 progesterone receptor Rattus norvegicus 62-64 7857875-6 1995 Treatment of OVX rats with estradiol (0.2 microgram/ml) restored tumor PR concentrations to the level of the control, whereas ER levels were increased to concentrations slightly higher than the control. Estradiol 27-36 progesterone receptor Rattus norvegicus 71-73 9603252-0 1998 Regulation of the progesterone receptor and estrogen receptor in decidua basalis by progesterone and estradiol during pregnancy. Estradiol 101-110 progesterone receptor Rattus norvegicus 18-39 9459197-6 1997 Treatment of ovariectomized rats with estradiol resulted in high PR levels in the myometrium and stroma cells but low PR immunoreactivity in the epithelial cells. Estradiol 38-47 progesterone receptor Rattus norvegicus 65-67 9459197-6 1997 Treatment of ovariectomized rats with estradiol resulted in high PR levels in the myometrium and stroma cells but low PR immunoreactivity in the epithelial cells. Estradiol 38-47 progesterone receptor Rattus norvegicus 118-120 7503800-1 1995 Treatment of immature 21-day-old female Sprague-Dawley rats with 17 beta-estradiol (E2) (0.5 microgram/rat) caused a significant increase in uterine wet weight, DNA synthesis, progesterone receptor (PR) binding, and peroxidase activity. Estradiol 65-82 progesterone receptor Rattus norvegicus 176-197 7503800-1 1995 Treatment of immature 21-day-old female Sprague-Dawley rats with 17 beta-estradiol (E2) (0.5 microgram/rat) caused a significant increase in uterine wet weight, DNA synthesis, progesterone receptor (PR) binding, and peroxidase activity. Estradiol 65-82 progesterone receptor Rattus norvegicus 199-201 7503800-1 1995 Treatment of immature 21-day-old female Sprague-Dawley rats with 17 beta-estradiol (E2) (0.5 microgram/rat) caused a significant increase in uterine wet weight, DNA synthesis, progesterone receptor (PR) binding, and peroxidase activity. Estradiol 84-86 progesterone receptor Rattus norvegicus 176-197 7503800-1 1995 Treatment of immature 21-day-old female Sprague-Dawley rats with 17 beta-estradiol (E2) (0.5 microgram/rat) caused a significant increase in uterine wet weight, DNA synthesis, progesterone receptor (PR) binding, and peroxidase activity. Estradiol 84-86 progesterone receptor Rattus norvegicus 199-201 9389534-3 1997 The present studies used in situ hybridization to ascertain the time course of PR mRNA regulation in the medial preoptic nucleus by 17beta-estradiol, determine the effective dose required to elicit a response, and compare the efficacy of 17beta-estradiol with a variety of estrogenic or antiestrogenic compounds. Estradiol 132-148 progesterone receptor Rattus norvegicus 79-81 9389534-4 1997 The first series of studies revealed that the treatment of ovariectomized rats with 17beta-estradiol resulted in an increase in PR expression within 2 h, after which it remained elevated until 10 h postinjection and then returned to baseline levels. Estradiol 84-100 progesterone receptor Rattus norvegicus 128-130 9389534-5 1997 When ovariectomized rats were injected with 25-1000 ng/kg of 17beta-estradiol and euthanized 6 h later, a dose-dependent increase in the level of PR mRNA was observed, with a maximal response at 1000 ng/kg and an EC50 of 93.5 ng/kg. Estradiol 61-77 progesterone receptor Rattus norvegicus 146-148 9389534-7 1997 17Beta-estradiol, diethylstilbestrol, and 17alpha-estradiol all significantly increased the level of PR mRNA, although the degree of induction varied with each compound. Estradiol 0-16 progesterone receptor Rattus norvegicus 101-103 9389534-9 1997 In contrast, when tamoxifen or raloxifene, but not ICI 182,780, was administered in the antagonist mode, a significant dose-related decrease in the estradiol-induced level of PR mRNA was seen in the preoptic area. Estradiol 148-157 progesterone receptor Rattus norvegicus 175-177 9389534-10 1997 The results of these studies clearly demonstrate that PR mRNA expression in the rat preoptic area is rapidly stimulated by a small dose of 17beta-estradiol. Estradiol 139-155 progesterone receptor Rattus norvegicus 54-56 7857875-11 1995 Levels of tumor mRNA of both ER and PR were inhibited by 4-OHA treatment in estradiol treated OVX rats. Estradiol 76-85 progesterone receptor Rattus norvegicus 36-38 8504742-2 1993 In the present study, we used immature ovariectomized rats to examine the regulation of PR gene expression and growth in the uterus by estradiol (E2) as well as hormonal modulators of E2 action, namely progesterone (P), the antiestrogen LY117018 (LY), and the antiprogestin RU486. Estradiol 135-144 progesterone receptor Rattus norvegicus 88-90 7932848-7 1994 Oral doses of 300 mg/kg of atrazine, simazine, or DACT significantly reduced expression of progesterone receptor binding in cytosol fractions prepared from uteri of ovariectomized rats injected sc with 1 microgram estradiol; 50 mg/kg triazine was not effective in this case. Estradiol 214-223 progesterone receptor Rattus norvegicus 91-112 8126569-3 1994 When applied 12 but not 24 hr after estradiol, the PR antisense treatment significantly reduced iordosis behavior, measured either as a reflex or in a mating behavior test. Estradiol 36-45 progesterone receptor Rattus norvegicus 51-53 7984148-3 1994 We found that a pulse of GnRH administered to gonadotrope-enriched pituitary cells cultured in medium containing charcoal-treated serum plus estradiol (E2) potentiated the LH secretory response to subsequent GnRH pulses, and this potentiation could be blocked by a PR antagonist, RU486, in the absence of progesterone. Estradiol 141-150 progesterone receptor Rattus norvegicus 265-267 1313194-4 1992 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), which exhibits a broad spectrum of antiestrogenic effects in the female rat uterus, inhibited the 17 beta-estradiol-induced increase in uterine wet weights, cytosolic and nuclear ER and PR levels, peroxidase activity, and EGF receptor binding activity. Estradiol 145-159 progesterone receptor Rattus norvegicus 230-232 1706263-8 1991 The increases in PR evoked by estradiol, cAMP, or IGF-I are markedly suppressed by treatment with antiestrogen (ICI 164,384) or the cyclic nucleotide-dependent protein kinase inhibitor H8 or the protein kinase A inhibitor PKI, indicating the involvement of the estrogen receptor and phosphorylation pathways in PR regulation by these three agents. Estradiol 30-39 progesterone receptor Rattus norvegicus 17-19 1874194-1 1991 In this study we have examined the effect of population density on the ability of 17 beta-estradiol (E2) to induce PRL mRNA, DNA synthesis, and progesterone receptor in GH4C1 pituitary tumor cells. Estradiol 82-99 progesterone receptor Rattus norvegicus 144-165 1706263-8 1991 The increases in PR evoked by estradiol, cAMP, or IGF-I are markedly suppressed by treatment with antiestrogen (ICI 164,384) or the cyclic nucleotide-dependent protein kinase inhibitor H8 or the protein kinase A inhibitor PKI, indicating the involvement of the estrogen receptor and phosphorylation pathways in PR regulation by these three agents. Estradiol 30-39 progesterone receptor Rattus norvegicus 311-313 1995287-4 1991 A "9 S" PR was observed in the cytosol and a "4-5 S" PR was found in the nuclear high salt, tungstate ions containing extract of estradiol-treated cells. Estradiol 129-138 progesterone receptor Rattus norvegicus 53-55 1995287-6 1991 The levels of PR, as measured by whole cell assay, were significantly increased when glial cells were cultured in the presence of 50 nM estradiol, as compared to nonestradiol-treated controls. Estradiol 136-145 progesterone receptor Rattus norvegicus 14-16 1995287-11 1991 This is the first demonstration of PR in rat glial cells, and we present evidence of its induction by estradiol in primary cultures. Estradiol 102-111 progesterone receptor Rattus norvegicus 35-37 1848992-6 1991 Treatment of OVX rats with 17 beta-estradiol (E2) alone or in combination with progesterone (P) caused a highly significant increase in beta-adrenergic and progesterone receptor levels, as well as tumor growth. Estradiol 27-44 progesterone receptor Rattus norvegicus 156-177 1949047-2 1991 Treatment of the animals with 17 beta-estradiol (0.33 mumol/kg X 2) caused an increase in uterine cytosolic and nuclear estrogen and progesterone receptor levels, uterine peroxidase activity, uterine wet weights and uterine epidermal growth factor (EGF) receptor binding activity and steady state EGF receptor mRNA levels. Estradiol 30-47 progesterone receptor Rattus norvegicus 133-154 34904297-10 2022 Finally, antagonism of either AVPV PGR or Src blocked the ability of PGR or Src activation to induce an LH surge in estradiol-primed ovx/adx rats. Estradiol 116-125 progesterone receptor Rattus norvegicus 69-72 3613575-0 1987 Estradiol-induced progesterone receptor synthesis in normal and diabetic ovariectomized rat uterus. Estradiol 0-9 progesterone receptor Rattus norvegicus 18-39 34904297-6 2022 Estradiol treatment increased the number of PGR immunopositive cells and PGR and Src colocalization. Estradiol 0-9 progesterone receptor Rattus norvegicus 44-47 3381634-0 1988 Effect of estradiol on the progesterone receptor and on morphological ultrastructures in the fetal and newborn uterus and ovary of the rat. Estradiol 10-19 progesterone receptor Rattus norvegicus 27-48 34904297-6 2022 Estradiol treatment increased the number of PGR immunopositive cells and PGR and Src colocalization. Estradiol 0-9 progesterone receptor Rattus norvegicus 73-76 34904297-7 2022 Furthermore, estradiol treatment increased the number of AVPV cells that had extranuclear PGR and Src in close proximity (< 40 nm). Estradiol 13-22 progesterone receptor Rattus norvegicus 90-93 2770296-7 1989 In the primary culture and in it"s first subculture the cells responded to estradiol with a 2-3-fold increase in progesterone receptor level. Estradiol 75-84 progesterone receptor Rattus norvegicus 113-134 2721449-4 1989 Uterine cells grown in ITS contain PgR levels that are near maximum (927 +/- 168 fmol/mg protein), and estradiol (0.1 nM; 24 h) causes a 10-50% increase in PgR. Estradiol 103-112 progesterone receptor Rattus norvegicus 156-159 2926313-11 1989 It is difficult to attribute this high tissue progesterone receptor concentration to oestradiol stimulation since, even at low levels, oestradiol induces tissue regression. Estradiol 135-145 progesterone receptor Rattus norvegicus 46-67 3381634-5 1988 Estradiol stimulated significantly the progesterone receptor in the fetal uterus at 20 days old. Estradiol 0-9 progesterone receptor Rattus norvegicus 39-60 3720665-7 1986 However, injection of orchiectomized males with 17 beta-estradiol significantly (P less than 0.05) increased progesterone receptor content to 208 +/- 24 fmol/mg DNA. Estradiol 48-65 progesterone receptor Rattus norvegicus 109-130 3448706-0 1987 Relationship between occupied form of nuclear estrogen receptor and cytosolic progesterone receptor or DNA synthesis in uteri of estradiol implanted rats. Estradiol 129-138 progesterone receptor Rattus norvegicus 78-99 3123757-4 1987 A single administration of 100 micrograms estradiol induced a transient decrease of ER and PRL-R, and an increase of PgR, in the DMBA-tumor. Estradiol 42-51 progesterone receptor Rattus norvegicus 117-120 3112670-0 1987 Priming action on progesterone receptor synthesis by estradiol and tamoxifen in the 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinoma. Estradiol 53-62 progesterone receptor Rattus norvegicus 18-39 3112670-1 1987 The priming action of estradiol and the antiestrogen tamoxifen (TMX) on progesterone receptor (PgR) synthesis has been investigated in the 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor model testing different priming times. Estradiol 22-31 progesterone receptor Rattus norvegicus 72-93 3720665-10 1986 The observation that 17 beta-estradiol modulates aortic progesterone receptor content indicates that rat aortic estrogen receptors are physiologically functional. Estradiol 21-38 progesterone receptor Rattus norvegicus 56-77 2936712-3 1986 Since estradiol induces progesterone receptor formation, we compared the ventilatory effect of the synthetic progestin medroxyprogesterone acetate (MPA) given in combination with estradiol with the effects of estradiol alone, MPA alone, or vehicle (saline) in ovariectomized rats. Estradiol 6-15 progesterone receptor Rattus norvegicus 24-45 3716757-3 1986 A single ip injection of 10 micrograms oestradiol-17 beta (E2) in ovariectomized and adrenalectomized rats resulted in a significant increase in pituitary weight and progesterone receptor (PgR) concentration. Estradiol 39-57 progesterone receptor Rattus norvegicus 166-187 3716757-3 1986 A single ip injection of 10 micrograms oestradiol-17 beta (E2) in ovariectomized and adrenalectomized rats resulted in a significant increase in pituitary weight and progesterone receptor (PgR) concentration. Estradiol 39-57 progesterone receptor Rattus norvegicus 189-192 3716757-3 1986 A single ip injection of 10 micrograms oestradiol-17 beta (E2) in ovariectomized and adrenalectomized rats resulted in a significant increase in pituitary weight and progesterone receptor (PgR) concentration. Estradiol 59-61 progesterone receptor Rattus norvegicus 166-187 3716757-3 1986 A single ip injection of 10 micrograms oestradiol-17 beta (E2) in ovariectomized and adrenalectomized rats resulted in a significant increase in pituitary weight and progesterone receptor (PgR) concentration. Estradiol 59-61 progesterone receptor Rattus norvegicus 189-192 3987619-1 1985 The rat uterus responds to estradiol (E2) and E2 benzoate stimulation with an increase in progesterone receptor production and with growth. Estradiol 27-36 progesterone receptor Rattus norvegicus 90-111 6971219-5 1981 Progesterone receptor levels were stimulated in the pituitary by repeated injection of 17 beta-estradiol, DM-EE2 and DB-EE2 and to a smaller degree by tamoxifen. Estradiol 87-104 progesterone receptor Rattus norvegicus 0-21 6745180-2 1984 Treatment of cells for 24 h with 1 nM 17 beta-estradiol in fresh medium led to a 3-fold increase in progesterone receptor concentration, but without fresh medium, no increase in progesterone receptors was observed. Estradiol 38-55 progesterone receptor Rattus norvegicus 100-121 6714156-2 1984 Progesterone receptor is induced within 1 day of 17 beta-estradiol treatment, with maximal response occurring after 2 days of treatment (300-500% of the control value). Estradiol 49-66 progesterone receptor Rattus norvegicus 0-21 6714156-3 1984 Induction of progesterone receptor occurred at physiological 17 beta-estradiol concentrations, with half-maximal response at about 5 X 10(-11) M. 17 beta-Estradiol induced the synthesis of a secreted protein (mol wt, 130,000) in a dose-dependent fashion. Estradiol 61-78 progesterone receptor Rattus norvegicus 13-34 6714156-3 1984 Induction of progesterone receptor occurred at physiological 17 beta-estradiol concentrations, with half-maximal response at about 5 X 10(-11) M. 17 beta-Estradiol induced the synthesis of a secreted protein (mol wt, 130,000) in a dose-dependent fashion. Estradiol 146-163 progesterone receptor Rattus norvegicus 13-34 6321624-5 1984 However, oestradiol administration caused an induction of these receptors in the immature rat uterus, together with a significant increase in the uterine weight, progesterone receptor level and peroxidase activity. Estradiol 9-19 progesterone receptor Rattus norvegicus 162-183 6890442-0 1982 Modulation of rat uterine progesterone receptor levels and peroxidase activity by tamoxifen citrate, LY117018, and estradiol. Estradiol 115-124 progesterone receptor Rattus norvegicus 26-47 6955558-2 1982 Progesterone receptor levels were barely detectable in tumors grown in male WF rats but were increased after castration or administration of 17 beta-estradiol. Estradiol 141-158 progesterone receptor Rattus norvegicus 0-21 6955558-4 1982 In tumors grown in intact female rats, both testosterone and dihydrotestosterone decreased progesterone receptor levels in a dose-dependent manner, and testosterone completely blocked the estradiol-induced increase in progesterone receptor levels in tumors from ovariectomized rats. Estradiol 188-197 progesterone receptor Rattus norvegicus 218-239 6489258-4 1984 ER is apparently functional at relatively low levels, since estradiol did induce PR synthesis, and cytosolic ER was reduced by estrogen administration. Estradiol 60-69 progesterone receptor Rattus norvegicus 81-83 6955558-8 1982 This fact plus the finding that testosterone only partially blocked the estradiol-induced increase in uterine progesterone receptor levels suggested stimulation of different cell types by testosterone and estradiol. Estradiol 72-81 progesterone receptor Rattus norvegicus 110-131 6955558-8 1982 This fact plus the finding that testosterone only partially blocked the estradiol-induced increase in uterine progesterone receptor levels suggested stimulation of different cell types by testosterone and estradiol. Estradiol 205-214 progesterone receptor Rattus norvegicus 110-131 7053987-0 1982 Differential stimulation by 17 beta-estradiol and synthetic estrogens of progesterone-receptor and of translocation of estrogen-receptor in rat pituitary and uterus. Estradiol 28-45 progesterone receptor Rattus norvegicus 73-94 32670203-3 2020 Estradiol from developing ovarian follicles acts on ERalpha-expressing kisspeptin neurons in the rostral periventricular region of the third ventricle (RP3V) to induce PGR expression, and kisspeptin release. Estradiol 0-9 progesterone receptor Rattus norvegicus 168-171 201053-1 1977 Daily injections of estradiol or the antiestrogen tamoxifen initially stimulate uterine weight increase and progesterone receptor synthesis, though continued tamoxifen fails to maintain the increased weight. Estradiol 20-29 progesterone receptor Rattus norvegicus 108-129 33901612-1 2021 Activation of progesterone receptor (PR) facilitates lordosis 36 to 48 hr after estradiol treatment, but induces concurrent inhibition (CI) when given with estradiol, or sequential inhibition (SI) when given subsequent to the faciliatory time interval. Estradiol 80-89 progesterone receptor Rattus norvegicus 14-35 33901612-1 2021 Activation of progesterone receptor (PR) facilitates lordosis 36 to 48 hr after estradiol treatment, but induces concurrent inhibition (CI) when given with estradiol, or sequential inhibition (SI) when given subsequent to the faciliatory time interval. Estradiol 80-89 progesterone receptor Rattus norvegicus 37-39 33901612-1 2021 Activation of progesterone receptor (PR) facilitates lordosis 36 to 48 hr after estradiol treatment, but induces concurrent inhibition (CI) when given with estradiol, or sequential inhibition (SI) when given subsequent to the faciliatory time interval. Estradiol 156-165 progesterone receptor Rattus norvegicus 14-35 33901612-1 2021 Activation of progesterone receptor (PR) facilitates lordosis 36 to 48 hr after estradiol treatment, but induces concurrent inhibition (CI) when given with estradiol, or sequential inhibition (SI) when given subsequent to the faciliatory time interval. Estradiol 156-165 progesterone receptor Rattus norvegicus 37-39