PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19497422-2 2009 Previously, we reported that TBT and TPT function as powerful agonists for peroxisome proliferator-activated receptor (PPAR) gamma and stimulate adipocyte differentiation via the PPARgamma signaling pathway. triphenyltin 37-40 peroxisome proliferator activated receptor gamma Homo sapiens 179-188 19497422-7 2009 All tested phenyltin compounds transcriptionally activated GAL-PPARgamma with an order of potency of TPT>DPT>monophenyltin. triphenyltin 101-104 peroxisome proliferator activated receptor gamma Homo sapiens 63-72 19497422-5 2009 TBT, TPT, diphenyltin (DPT), and tetrabutyltin (TeBT) blocked the binding of [(3)H]Rosi to PPARgamma in a competitive manner, and all tested organotin compounds except monobutyltin blocked the binding of [(14)C]TPT to PPARgamma in a competitive manner. triphenyltin 5-8 peroxisome proliferator activated receptor gamma Homo sapiens 91-100 18670157-8 2008 Recently, organotin compounds including TBT and TPT were identified as nanomolar agonists for retinoid X receptor (RXR) and peroxisome proliferator-activated receptor (PPAR) gamma, which are members of the nuclear receptor superfamily. triphenyltin 48-51 peroxisome proliferator activated receptor gamma Homo sapiens 124-179 23123459-6 2012 TBT and TPT are dual agonists of retinoid X receptor (RXR) and peroxisome proliferator-activated receptor gamma (PPARgamma); they also induce the differentiation of adipocytes in vitro and in vivo, probably through PPARgamma activation, suggesting that they may work as obesogens. triphenyltin 8-11 peroxisome proliferator activated receptor gamma Homo sapiens 63-111 25985376-8 2015 We used a PPARgamma/RXRalpha C432A heterodimer to determine whether TBT and TPT could activate the heterodimer by binding to PPARgamma. triphenyltin 76-79 peroxisome proliferator activated receptor gamma Homo sapiens 125-134 25985376-9 2015 We found that TBT and TPT activated the PPARgamma/RXRalpha C432A heterodimer, which suggests that both compounds can activate the heterodimer through PPARgamma. triphenyltin 22-25 peroxisome proliferator activated receptor gamma Homo sapiens 40-49 25985376-9 2015 We found that TBT and TPT activated the PPARgamma/RXRalpha C432A heterodimer, which suggests that both compounds can activate the heterodimer through PPARgamma. triphenyltin 22-25 peroxisome proliferator activated receptor gamma Homo sapiens 150-159 25985376-1 2015 Organotins, such as tributyltin (TBT) and triphenyltin (TPT), may disrupt endocrine activity in mammals arising from their ability to act as ligands for the retinoid X receptor (RXR) and the peroxisome proliferator-activated receptor gamma (PPARgamma). triphenyltin 42-54 peroxisome proliferator activated receptor gamma Homo sapiens 191-239 25985376-1 2015 Organotins, such as tributyltin (TBT) and triphenyltin (TPT), may disrupt endocrine activity in mammals arising from their ability to act as ligands for the retinoid X receptor (RXR) and the peroxisome proliferator-activated receptor gamma (PPARgamma). triphenyltin 42-54 peroxisome proliferator activated receptor gamma Homo sapiens 241-250 25985376-1 2015 Organotins, such as tributyltin (TBT) and triphenyltin (TPT), may disrupt endocrine activity in mammals arising from their ability to act as ligands for the retinoid X receptor (RXR) and the peroxisome proliferator-activated receptor gamma (PPARgamma). triphenyltin 56-59 peroxisome proliferator activated receptor gamma Homo sapiens 191-239 25985376-1 2015 Organotins, such as tributyltin (TBT) and triphenyltin (TPT), may disrupt endocrine activity in mammals arising from their ability to act as ligands for the retinoid X receptor (RXR) and the peroxisome proliferator-activated receptor gamma (PPARgamma). triphenyltin 56-59 peroxisome proliferator activated receptor gamma Homo sapiens 241-250 25687586-1 2015 Organotin compounds such as triphenyltin (TPT) and tributyltin (TBT) act as endocrine disruptors through the peroxisome proliferator-activated receptor gamma (PPARgamma) signaling pathway. triphenyltin 28-40 peroxisome proliferator activated receptor gamma Homo sapiens 109-157 25687586-1 2015 Organotin compounds such as triphenyltin (TPT) and tributyltin (TBT) act as endocrine disruptors through the peroxisome proliferator-activated receptor gamma (PPARgamma) signaling pathway. triphenyltin 28-40 peroxisome proliferator activated receptor gamma Homo sapiens 159-168 23123459-6 2012 TBT and TPT are dual agonists of retinoid X receptor (RXR) and peroxisome proliferator-activated receptor gamma (PPARgamma); they also induce the differentiation of adipocytes in vitro and in vivo, probably through PPARgamma activation, suggesting that they may work as obesogens. triphenyltin 8-11 peroxisome proliferator activated receptor gamma Homo sapiens 113-122 23123459-6 2012 TBT and TPT are dual agonists of retinoid X receptor (RXR) and peroxisome proliferator-activated receptor gamma (PPARgamma); they also induce the differentiation of adipocytes in vitro and in vivo, probably through PPARgamma activation, suggesting that they may work as obesogens. triphenyltin 8-11 peroxisome proliferator activated receptor gamma Homo sapiens 215-224