PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19567096-4 2009 RESULTS: The serum MIF, TNF-alpha, and IL-6 levels of the DM, DPN, and DPNP groups were all significantly higher than those of the control group (P < 0. dpn 62-65 interleukin 6 Homo sapiens 39-43 28512447-6 2017 Given exercise induces IL-6 myokine signaling, and exercise has been shown to elicit numerous beneficial effects for the treatment of DPN, a causal link has been suggested. dpn 134-137 interleukin 6 Homo sapiens 23-27 28512447-9 2017 Collectively, studies suggest that IL-6, when administered in a low-dose pulsatile strategy to mimic the body"s natural response to exercise, may prove to be an effective treatment for the protection and/or restoration of peripheral nerve function in DPN. dpn 251-254 interleukin 6 Homo sapiens 35-39 28512447-10 2017 This review highlights the studies supporting this assertion and provides rationale for continued investigation of IL-6 for the treatment of DPN. dpn 141-144 interleukin 6 Homo sapiens 115-119 27981790-4 2017 Compared with the other two groups, the DPN group had higher expression of TLR4, MyD88, phosphorylated IkappaB, TNF-alpha, and IL-6, but significantly lower levels of caveolin-1 and total IkappaB in monocytes. dpn 40-43 interleukin 6 Homo sapiens 127-131 32996080-9 2021 The levels of inflammatory factors (TNF-alpha, IL-1beta, and IL-6) were elevated in DPN model. dpn 84-87 interleukin 6 Homo sapiens 61-65 19567096-9 2009 CONCLUSIONS: The serum pro-inflammatory cytokines MIF, TNF-alpha, and IL-6 levels play an important role in the pathogenesis of DM and DPN, but may not play an important role in the development of DPNP. dpn 135-138 interleukin 6 Homo sapiens 70-74