PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10188982-8 1999 Furthermore, administration of aminoguanidine (300 mg kg(-1), s.c.), a relatively selective inhibitor of iNOS activity, 60 min before sustained ischaemia also abolished the delayed protection afforded by ischaemic preconditioning (infarct size 40.0+/-6.0%). pimagedine 31-45 nitric oxide synthase, inducible Oryctolagus cuniculus 105-109 11773821-2 2002 An important effect of the neuroprotective substance aminoguanidine (AG) is the inhibition of inducible nitric oxide synthase (iNOS), a perpetrator of focal ischemic damage. pimagedine 53-67 nitric oxide synthase, inducible Oryctolagus cuniculus 94-125 11773821-2 2002 An important effect of the neuroprotective substance aminoguanidine (AG) is the inhibition of inducible nitric oxide synthase (iNOS), a perpetrator of focal ischemic damage. pimagedine 53-67 nitric oxide synthase, inducible Oryctolagus cuniculus 127-131 7514189-4 1994 NG-monomethyl-L-arginine (L-NMMA), which blocks the activity of both constitutive and inducible nitric oxide synthase (cNOS and iNOS), aminoguanidine, a recently described selective iNOS inhibitor, dexamethasone, or cycloheximide abolished the release of NO2- and attenuated the exaggerated BK-induced PGE2 production. pimagedine 135-149 nitric oxide synthase, inducible Oryctolagus cuniculus 86-117 30086070-8 2018 The iNOS and ET-1 inhibitors, aminoguanidine (20 mg/kg) and PD-142893 (0.02 mg/kg), respectively, induced significant improvements in vascular reactivity and organ perfusion and stabilized the hemodynamic parameters in rabbits subjected to endotoxic shock. pimagedine 30-44 nitric oxide synthase, inducible Oryctolagus cuniculus 4-8 10443512-0 1999 Aminoguanidine inhibits inducible NOS and reverses cardiac dysfunction late after ischemia and reperfusion--implications for iNOS-mediated myocardial stunning. pimagedine 0-14 nitric oxide synthase, inducible Oryctolagus cuniculus 125-129 10443512-6 1999 However, AMG significantly inhibited iNOS activity, significantly improved left-ventricular maximum + dP/dt and decreased LVEDP, whereas administration of L-arginine reduced + dP/dt and slightly increased LVEDP, compared to AMG-treated animals. pimagedine 9-12 nitric oxide synthase, inducible Oryctolagus cuniculus 37-41