PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11358991-3	2001	The NO synthase inhibitors aminoguanidine and N(G)-nitro-L-arginine methyl ester blocked nuclear accumulation of activator protein-1 (AP-1) and nuclear factor (NF)-kappaB in both polymorphonuclear (PMN) and mononuclear leukocytes and inhibited IL-8 mRNA expression and IL-8 release by approximately 90% in response to IL-1beta and TNF-alpha.	pimagedine	27-41	C-X-C motif chemokine ligand 8	Homo sapiens	244-248	
21907687-12	2012	Pyridoxamine and aminoguanidine inhibited the endogenous CML formation and the increased RAGE, PAI-1, IL-8, IL-6, and CRP expression.	pimagedine	17-31	C-X-C motif chemokine ligand 8	Homo sapiens	102-106	
11358991-3	2001	The NO synthase inhibitors aminoguanidine and N(G)-nitro-L-arginine methyl ester blocked nuclear accumulation of activator protein-1 (AP-1) and nuclear factor (NF)-kappaB in both polymorphonuclear (PMN) and mononuclear leukocytes and inhibited IL-8 mRNA expression and IL-8 release by approximately 90% in response to IL-1beta and TNF-alpha.	pimagedine	27-41	C-X-C motif chemokine ligand 8	Homo sapiens	269-273	
9820546-4	1998	Both aminoguanidine and L-NAME blocked the induction of IL-8 mRNA by LPS.	pimagedine	5-19	C-X-C motif chemokine ligand 8	Homo sapiens	56-60	
9820546-3	1998	The NO synthase inhibitors aminoguanidine and NG-nitro-L-arginine methyl ester (L-NAME) blocked IL-8 release by approximately 90% in response to LPS (1 microg/ml), but did not affect the production of IL-1beta or TNF-alpha.	pimagedine	27-41	C-X-C motif chemokine ligand 8	Homo sapiens	96-100