PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8682655-2 1996 Macrophage activation was achieved by cell incubation with phorbol myristate acetate (PMA) for 24 h at 37 degrees C, and was determined as: a) PMA concentration-dependent increment in the release of beta-glucuronidase, b) decrement in the procoagulant activity, and c) increment in the release of superoxides from the cells. Tetradecanoylphorbol Acetate 59-84 glucuronidase beta Homo sapiens 199-217 8682655-2 1996 Macrophage activation was achieved by cell incubation with phorbol myristate acetate (PMA) for 24 h at 37 degrees C, and was determined as: a) PMA concentration-dependent increment in the release of beta-glucuronidase, b) decrement in the procoagulant activity, and c) increment in the release of superoxides from the cells. Tetradecanoylphorbol Acetate 86-89 glucuronidase beta Homo sapiens 199-217 8682655-2 1996 Macrophage activation was achieved by cell incubation with phorbol myristate acetate (PMA) for 24 h at 37 degrees C, and was determined as: a) PMA concentration-dependent increment in the release of beta-glucuronidase, b) decrement in the procoagulant activity, and c) increment in the release of superoxides from the cells. Tetradecanoylphorbol Acetate 143-146 glucuronidase beta Homo sapiens 199-217 8206872-5 1994 Phorbol myristate acetate (PMA) and 1-oleoyl-2-acetyl-sn-glycerol induced the release of lactoferrin alone at concentrations of Ca2+ below 0.5 microM while they induced the release of both beta-glucuronidase and lactoferrin at higher Ca2+ concentrations, indicating that the degranulation induced by PA10 is not mediated by diacylglycerol which might be formed from PA. Tetradecanoylphorbol Acetate 0-25 glucuronidase beta Homo sapiens 189-207 8206872-5 1994 Phorbol myristate acetate (PMA) and 1-oleoyl-2-acetyl-sn-glycerol induced the release of lactoferrin alone at concentrations of Ca2+ below 0.5 microM while they induced the release of both beta-glucuronidase and lactoferrin at higher Ca2+ concentrations, indicating that the degranulation induced by PA10 is not mediated by diacylglycerol which might be formed from PA. Tetradecanoylphorbol Acetate 27-30 glucuronidase beta Homo sapiens 189-207 1663527-2 1991 PMN were stimulated by fMet-Leu-Phe (FMLP) or phorbol myristate acetate (PMA) to elicit chemotaxis, extracellular release of beta-glucuronidase (BGL) and superoxide anion (SOA) production. Tetradecanoylphorbol Acetate 46-71 glucuronidase beta Homo sapiens 125-143 1892735-4 1991 On the other hand, direct stimulation of protein kinase C with phorbol myristate acetate (PMA) revealed a subnormal stimulation of beta-glucuronidase exocytosis in CF neutrophils. Tetradecanoylphorbol Acetate 63-88 glucuronidase beta Homo sapiens 131-149 1892735-4 1991 On the other hand, direct stimulation of protein kinase C with phorbol myristate acetate (PMA) revealed a subnormal stimulation of beta-glucuronidase exocytosis in CF neutrophils. Tetradecanoylphorbol Acetate 90-93 glucuronidase beta Homo sapiens 131-149 1663527-2 1991 PMN were stimulated by fMet-Leu-Phe (FMLP) or phorbol myristate acetate (PMA) to elicit chemotaxis, extracellular release of beta-glucuronidase (BGL) and superoxide anion (SOA) production. Tetradecanoylphorbol Acetate 73-76 glucuronidase beta Homo sapiens 125-143 1663527-2 1991 PMN were stimulated by fMet-Leu-Phe (FMLP) or phorbol myristate acetate (PMA) to elicit chemotaxis, extracellular release of beta-glucuronidase (BGL) and superoxide anion (SOA) production. Tetradecanoylphorbol Acetate 73-76 glucuronidase beta Homo sapiens 145-148 3475147-2 1987 PMA, PDBu and the diacylglycerol, OAG, all caused a dose-dependent and slow (max by 15 min) release of small amounts of lysozyme with much less beta-glucuronidase and no release of cytoplasmic lactate dehydrogenase. Tetradecanoylphorbol Acetate 0-3 glucuronidase beta Homo sapiens 144-162 2547940-4 1989 Cells exposed to dexamethasone (10(-6) M) released equal or greater quantities of the lysosomal enzymes, lysozyme and beta-glucuronidase in response to formylmethionyl-leucyl-phenylalanine, serum activated zymosan, and the tumor promoting phorbol diester 12-O-tetradecanoylphorbol-13-acetate compared to controls. Tetradecanoylphorbol Acetate 255-291 glucuronidase beta Homo sapiens 118-136 6430792-5 1984 PMA activation in the presence of cytochalasin B augments the release of lysozyme and initiates the release of beta glucuronidase through recruitment of the azurophilic granule but has no incremental effect on the release of vitamin B12-binding protein and histaminase observed with PMA alone. Tetradecanoylphorbol Acetate 0-3 glucuronidase beta Homo sapiens 111-129 3023484-10 1986 Although calcium ionophore (2 X 10(-6) M) caused enzyme release (24.2% release of beta-glucuronidase, 29.4% release of arylsulfatase), this release was inhibited by the addition of TPA. Tetradecanoylphorbol Acetate 181-184 glucuronidase beta Homo sapiens 82-100 322507-2 1977 Phorbol myristate acetate (PMA, 2 to 100 ng/ml) and ionophore A23187 (10(-7) to 10(-6) M) cause human neutrophils to release up to 50% of the granule-associated enzyme lysozyme extracellularly without release of beta-glucuronidase or the cytoplasmic enzyme LDH. Tetradecanoylphorbol Acetate 0-25 glucuronidase beta Homo sapiens 212-230 7126637-11 1982 Secretion of beta-glucuronidase in response to N-formylmethionylleucylphenylalanine was also diminished by increasing the time of exposure to the initial stimulus of phorbol myristate acetate. Tetradecanoylphorbol Acetate 166-191 glucuronidase beta Homo sapiens 13-31 6272736-10 1981 General activating and cytotoxic effects of TPA were monitored by determining release of lysozyme, beta-glucuronidase and lactate dehydrogenase. Tetradecanoylphorbol Acetate 44-47 glucuronidase beta Homo sapiens 99-117 6717062-7 1984 In all cell lines, exposure to TPA resulted in an approximately two-fold increase in acid phosphatase and beta-glucuronidase activity. Tetradecanoylphorbol Acetate 31-34 glucuronidase beta Homo sapiens 106-124 322507-2 1977 Phorbol myristate acetate (PMA, 2 to 100 ng/ml) and ionophore A23187 (10(-7) to 10(-6) M) cause human neutrophils to release up to 50% of the granule-associated enzyme lysozyme extracellularly without release of beta-glucuronidase or the cytoplasmic enzyme LDH. Tetradecanoylphorbol Acetate 27-30 glucuronidase beta Homo sapiens 212-230 1158973-4 1975 Beta-glucuronidase was not released in significant amounts from PMN"s exposed to PMA alone, in the absence of stimuli such as zymosan or C5a. Tetradecanoylphorbol Acetate 81-84 glucuronidase beta Homo sapiens 0-18 1158973-7 1975 Enhancement of lysosomal enzyme (beta-glucuronidase) release by PMA appears to be independent of effects on release of specific granule enzymes (lysozyme), but rather is likely due to PMA-induced elevations of cellular cGMP. Tetradecanoylphorbol Acetate 64-67 glucuronidase beta Homo sapiens 33-51 1158973-7 1975 Enhancement of lysosomal enzyme (beta-glucuronidase) release by PMA appears to be independent of effects on release of specific granule enzymes (lysozyme), but rather is likely due to PMA-induced elevations of cellular cGMP. Tetradecanoylphorbol Acetate 184-187 glucuronidase beta Homo sapiens 33-51