PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19124542-6	2009	In contrast, the phorbol ester PMA (phorbol-12-myristate-13-acetate, a pharmacological mimic of the downstream mediator diacylglycerol in alpha-adrenergic signalling), caused continuous PKD-dependent HDAC5-GFP nuclear efflux and maintained PKD1-mPlum redistribution.	Tetradecanoylphorbol Acetate	36-67	protein kinase D1	Mus musculus	186-189	
21047949-3	2011	In this study, we demonstrate that MA-10 mouse Leydig tumor cells express several PKC isoforms to varying levels and that the activation of PKC signaling, by phorbol 12-myristate 13-acetate (PMA) elevated the expression and phosphorylation of PKCalpha, -delta, -epsilon, and -mu/protein kinase D (PKD).	Tetradecanoylphorbol Acetate	158-189	protein kinase D1	Mus musculus	297-300	
21047949-3	2011	In this study, we demonstrate that MA-10 mouse Leydig tumor cells express several PKC isoforms to varying levels and that the activation of PKC signaling, by phorbol 12-myristate 13-acetate (PMA) elevated the expression and phosphorylation of PKCalpha, -delta, -epsilon, and -mu/protein kinase D (PKD).	Tetradecanoylphorbol Acetate	191-194	protein kinase D1	Mus musculus	297-300	
21047949-6	2011	PKD was capable of controlling PMA and cAMP/PKA-mediated synergism involved in the steroidogenic response.	Tetradecanoylphorbol Acetate	31-34	protein kinase D1	Mus musculus	0-3	
19124542-6	2009	In contrast, the phorbol ester PMA (phorbol-12-myristate-13-acetate, a pharmacological mimic of the downstream mediator diacylglycerol in alpha-adrenergic signalling), caused continuous PKD-dependent HDAC5-GFP nuclear efflux and maintained PKD1-mPlum redistribution.	Tetradecanoylphorbol Acetate	31-34	protein kinase D1	Mus musculus	186-189	
19124542-7	2009	In the absence of expressed HDAC, PMA increased histone H3 acetylation and increased MEF2 reporter activity in a PKD-dependent manner, consistent with PKD phosphorylation of endogenous HDAC(s) and reduced nuclear HDAC activity due to HDAC nuclear efflux.	Tetradecanoylphorbol Acetate	34-37	protein kinase D1	Mus musculus	113-116	
19124542-7	2009	In the absence of expressed HDAC, PMA increased histone H3 acetylation and increased MEF2 reporter activity in a PKD-dependent manner, consistent with PKD phosphorylation of endogenous HDAC(s) and reduced nuclear HDAC activity due to HDAC nuclear efflux.	Tetradecanoylphorbol Acetate	34-37	protein kinase D1	Mus musculus	151-154	
16098040-5	2005	Elevated extracellular calcium and acute 12-O-tetradecanoylphorbol-13-acetate (TPA) treatments induced differentiation and triggered a downmodulation of PKD levels, autophosphorylation at serine 916, and activity.	Tetradecanoylphorbol Acetate	41-77	protein kinase D1	Mus musculus	153-156	
16098040-5	2005	Elevated extracellular calcium and acute 12-O-tetradecanoylphorbol-13-acetate (TPA) treatments induced differentiation and triggered a downmodulation of PKD levels, autophosphorylation at serine 916, and activity.	Tetradecanoylphorbol Acetate	79-82	protein kinase D1	Mus musculus	153-156	
16098040-6	2005	Chronic TPA treatment stimulated proliferation and resulted in a recovery of PKD levels, autophosphorylation, and activity.	Tetradecanoylphorbol Acetate	8-11	protein kinase D1	Mus musculus	77-80