PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12739001-2	2003	When K562 cells were induced to differentiate into the megakaryocyte lineage by treatment with TPA, the expression of the c-ets-1, Fli-1 and TEL2 genes was increased, and that of the TEL gene was decreased at the onset of differentiation.	Tetradecanoylphorbol Acetate	95-98	ETS proto-oncogene 1, transcription factor	Homo sapiens	122-129	
15889157-6	2005	Further, we provide evidence that cotransfection with Ets-1 and constitutively active Mek-1 in HTLV-1-negative transformed T cells with stimulation by PMA/ionomycin not only resulted in a robust induction of PTHrP P3 but also formed a complex with ETS-1/P3 EBS similar to that in ATLL cells.	Tetradecanoylphorbol Acetate	151-154	ETS proto-oncogene 1, transcription factor	Homo sapiens	54-59	
15889157-6	2005	Further, we provide evidence that cotransfection with Ets-1 and constitutively active Mek-1 in HTLV-1-negative transformed T cells with stimulation by PMA/ionomycin not only resulted in a robust induction of PTHrP P3 but also formed a complex with ETS-1/P3 EBS similar to that in ATLL cells.	Tetradecanoylphorbol Acetate	151-154	ETS proto-oncogene 1, transcription factor	Homo sapiens	248-253	
9178763-6	1997	Stimulation of MMP-1 promoter by 12-O-tetradecanoyl phorbol-13-acetate and okadaic acid was differentially augmented by ETS-1 and ERGB/Fli-1, and abrogated by PU.1.	Tetradecanoylphorbol Acetate	33-70	ETS proto-oncogene 1, transcription factor	Homo sapiens	120-125	
12058964-6	2002	The Ets-1 protein was only detected in MDA-MB-231 cells and its level increased following TPA stimulation.	Tetradecanoylphorbol Acetate	90-93	ETS proto-oncogene 1, transcription factor	Homo sapiens	4-9	
9190901-5	1997	We have previously shown that ETS1 can transactivate GM-CSF in Jurkat T cells, but only after the cells have been stimulated by treatment with PMA and ionomycin, agents that mimic T cell activation.	Tetradecanoylphorbol Acetate	143-146	ETS proto-oncogene 1, transcription factor	Homo sapiens	30-34	
9190901-6	1997	Thus we proposed that ETS1, which is expressed constitutively in Jurkat cells, may act in concert with PMA/ionomycin inducible factors.	Tetradecanoylphorbol Acetate	103-106	ETS proto-oncogene 1, transcription factor	Homo sapiens	22-26	
9156339-2	1997	Induction of morphogenesis by TPA is accompanied by increased activity of the collagenase gene transcription factors, ETS1 and API, and the elaboration of collagenase by the endothelial cells.	Tetradecanoylphorbol Acetate	30-33	ETS proto-oncogene 1, transcription factor	Homo sapiens	118-122	
9156339-7	1997	Further studies showed that inhibition of TPA-induced endothelial cell morphogenesis by oxLDL is correlated with suppression of the protein kinase C (PKC) and ETS1/AP1 activities.	Tetradecanoylphorbol Acetate	42-45	ETS proto-oncogene 1, transcription factor	Homo sapiens	159-163	
9190210-5	1997	Overexpression of Ets-1 augments the response to PMA/ionomycin and this is reduced by mutation of EBS4.	Tetradecanoylphorbol Acetate	49-52	ETS proto-oncogene 1, transcription factor	Homo sapiens	18-23	
9190210-7	1997	This activation is only partly affected by mutation of EBS4, and a mutant promoter that binds Ets-1, but not Elf-1, at the EBS4 site responds to PMA/ionomycin as efficiently as the wild-type.	Tetradecanoylphorbol Acetate	145-148	ETS proto-oncogene 1, transcription factor	Homo sapiens	94-99	
7478534-0	1995	ETS1 transactivates the human GM-CSF promoter in Jurkat T cells stimulated with PMA and ionomycin.	Tetradecanoylphorbol Acetate	80-83	ETS proto-oncogene 1, transcription factor	Homo sapiens	0-4	
7478534-9	1995	The GM-CSF promoter, modified in this way to be ETS1 specific, is fully responsive to PMA/ionomycin induction, in addition to ETS1 transactivation in the presence of PMA and ionomycin.	Tetradecanoylphorbol Acetate	86-89	ETS proto-oncogene 1, transcription factor	Homo sapiens	48-52	
7478534-9	1995	The GM-CSF promoter, modified in this way to be ETS1 specific, is fully responsive to PMA/ionomycin induction, in addition to ETS1 transactivation in the presence of PMA and ionomycin.	Tetradecanoylphorbol Acetate	166-169	ETS proto-oncogene 1, transcription factor	Homo sapiens	48-52	
7478534-9	1995	The GM-CSF promoter, modified in this way to be ETS1 specific, is fully responsive to PMA/ionomycin induction, in addition to ETS1 transactivation in the presence of PMA and ionomycin.	Tetradecanoylphorbol Acetate	166-169	ETS proto-oncogene 1, transcription factor	Homo sapiens	126-130	
7937106-8	1994	Consistent with the in vitro results, point mutations in p68c-ets-1 that decrease binding activity to EBS abrogate its ability to transactivate reporter plasmids carrying either the TPA Oncogene Response Unit of the Polyoma virus enhancer (TORU) or a sequence derived from the HTLV-1 LTR.	Tetradecanoylphorbol Acetate	182-185	ETS proto-oncogene 1, transcription factor	Homo sapiens	62-67