PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10595652-7	1999	These data indicate that PMA-induced and PKC-dependent expression of COX-2 requires mainly activation of ERK 1/2 among MAPKs, while activation of both ERK1/2 and p38 or possibly of all three families of MAPKs is necessary for vanadate-induced and PTK-dependent expression of COX-2.	Tetradecanoylphorbol Acetate	25-28	EPH receptor A8	Homo sapiens	247-250	
7585980-3	1995	Using a src family protein tyrosine kinase (PTK) inhibitor, herbimycin A, the cell proliferation induced by the anti-CD6 mAb, IOR-T1, in TPA-treated T cells were effectively abolished.	Tetradecanoylphorbol Acetate	137-140	EPH receptor A8	Homo sapiens	19-42	
7585980-3	1995	Using a src family protein tyrosine kinase (PTK) inhibitor, herbimycin A, the cell proliferation induced by the anti-CD6 mAb, IOR-T1, in TPA-treated T cells were effectively abolished.	Tetradecanoylphorbol Acetate	137-140	EPH receptor A8	Homo sapiens	44-47	
7488237-2	1995	The increases in activities of both protein tyrosine phosphatase (PTP) and protein tyrosine kinase (PTK) have been reported to be associated with the TPA-induced differentiation of HL-60 leukemia cells.	Tetradecanoylphorbol Acetate	150-153	EPH receptor A8	Homo sapiens	75-98	
7488237-2	1995	The increases in activities of both protein tyrosine phosphatase (PTP) and protein tyrosine kinase (PTK) have been reported to be associated with the TPA-induced differentiation of HL-60 leukemia cells.	Tetradecanoylphorbol Acetate	150-153	EPH receptor A8	Homo sapiens	100-103	
7488237-5	1995	On the other hand, although TPA induced a transient slight increase in PTK activity (1.4-fold) at 60 min, four PTK inhibitors (genistein, herbimycin A, tyrphostin-23 and quercetin) had different effects on the TPA-induced release of cell surface proteoglycan.	Tetradecanoylphorbol Acetate	28-31	EPH receptor A8	Homo sapiens	71-74	
7488237-7	1995	Taken together, these observations suggest that both PTP and PTK activities were increased in SW620 cells in response to TPA; however, the activation of PTP seems to be preferentially required for the TPA-induced differentiation of SW620 human colon cancer cells.	Tetradecanoylphorbol Acetate	121-124	EPH receptor A8	Homo sapiens	61-64