PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11380624-5	2001	Similarly, TPA-induced PLD activation was reduced in Btk deficient cells, but unaffected in Lyn deficient cells.	Tetradecanoylphorbol Acetate	11-14	Bruton tyrosine kinase	Gallus gallus	53-56	
11380624-6	2001	Finally, in cells deficient in the PLC-gamma2, one of the phosphorylated substrates regulated by Syk and Btk, TPA-induced PLD activation, as well as phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolysis was remarkably reduced.	Tetradecanoylphorbol Acetate	110-113	Bruton tyrosine kinase	Gallus gallus	105-108	
11380624-7	2001	CONCLUSIONS: We demonstrated that the Syk, Btk and PLC-gamma2 pathways are required for TPA-induced PLD activation in DT40 cells.	Tetradecanoylphorbol Acetate	88-91	Bruton tyrosine kinase	Gallus gallus	43-46