PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10993214-4 2000 Although translocation of p47phox and p67phox to the membrane fraction by PMA-stimulation of intact and GCSF-treated neutrophils occurred in parallel with O2- production, that of CB-treated neutrophils by PMA-stimulation was not always proportional to O2- production. Tetradecanoylphorbol Acetate 74-77 neutrophil cytosolic factor 2 Homo sapiens 38-45 10540223-10 1999 In subcellular fractions, Rac2 was found to translocate, along with p47phox and p67phox, from cytosol to plasma membrane-associated fractions following phorbol myristate acetate stimulation, while RhoGDI remained within cytosolic fractions. Tetradecanoylphorbol Acetate 152-177 neutrophil cytosolic factor 2 Homo sapiens 80-87 1848559-6 1991 Using the PKC activator phorbol myristate acetate (PMA) as the agonist, we found that activation of the respiratory burst oxidase was associated with translocation of cytosolic p47-phox and p67-phox to the plasma membrane as well as redistribution of p47-phox to the Triton-insoluble cytoskeleton. Tetradecanoylphorbol Acetate 24-49 neutrophil cytosolic factor 2 Homo sapiens 190-198 9931304-1 1999 Phosphorylation of p67phox was shown to increase two- to three-fold upon stimulation by PMA, N-formylmethionyl-leucylphenylalanine or serum-opsonized zymosan. Tetradecanoylphorbol Acetate 88-91 neutrophil cytosolic factor 2 Homo sapiens 19-26 9794433-6 1998 4) In PMA-stimulated B cells from an X91+ CGD patient in which p22phox was normally expressed and gp91phox was present but lacked five amino acids, translocation of p47phox to the membranes was unaffected, but p67phox and p40phox were poorly translocated, and the production of O2- was greatly reduced with respect to that by normal B cells. Tetradecanoylphorbol Acetate 6-9 neutrophil cytosolic factor 2 Homo sapiens 210-217 7744791-7 1995 Moreover, although phorbol 12-myristate 13-acetate stimulated both the stable translocation of p47phox and p67phox and sustained NADPH oxidase activity, it did not stimulate p21rac2 translocation. Tetradecanoylphorbol Acetate 19-50 neutrophil cytosolic factor 2 Homo sapiens 107-114 8270871-3 1994 Stimulation of human neutrophils with PMA greatly increased O2(-)-generating activity and caused considerable translocation of the cytosolic components p47phox and p67phox. Tetradecanoylphorbol Acetate 38-41 neutrophil cytosolic factor 2 Homo sapiens 164-171 8257426-2 1993 Evidence has been accumulated that in phorbol 12-myristate 13-acetate (PMA)-stimulated neutrophils, the translocation to the plasma membrane of the cytosolic components p47phox and p67phox and the phosphorylation of p47phox are essential steps in activation of NADPH oxidase. Tetradecanoylphorbol Acetate 71-74 neutrophil cytosolic factor 2 Homo sapiens 181-188 8257426-8 1993 That the phosphorylated p67 protein we identified in immunoprecipitation experiments was p67phox was confirmed by the observation that no phosphorylated band of 67 kDa was immunoprecipitated from the cytosol and membranes of PMA-stimulated neutrophils from a p67phox-deficient chronic granulomatous disease patient. Tetradecanoylphorbol Acetate 225-228 neutrophil cytosolic factor 2 Homo sapiens 89-96 8182143-4 1994 In PMA-stimulated neutrophils and in a cell-free translocation assay with neutrophil membranes and cytosol, the association of the cytosolic proteins p47-phox and p67-phox with the membrane fraction of the patient was strongly disturbed. Tetradecanoylphorbol Acetate 3-6 neutrophil cytosolic factor 2 Homo sapiens 163-171 8141770-3 1994 Activation of superoxide production by phorbol 12-myristate 13-acetate or formylmethionyl-leucyl-phenylalanine in whole cells, and by SDS in the cell-free assay, led to the dissociation of some of the p21rac2 from rhoGDI and its movement to the plasma membrane together with p47phox and p67phox. Tetradecanoylphorbol Acetate 39-70 neutrophil cytosolic factor 2 Homo sapiens 287-294 8257426-2 1993 Evidence has been accumulated that in phorbol 12-myristate 13-acetate (PMA)-stimulated neutrophils, the translocation to the plasma membrane of the cytosolic components p47phox and p67phox and the phosphorylation of p47phox are essential steps in activation of NADPH oxidase. Tetradecanoylphorbol Acetate 38-69 neutrophil cytosolic factor 2 Homo sapiens 181-188 1848559-6 1991 Using the PKC activator phorbol myristate acetate (PMA) as the agonist, we found that activation of the respiratory burst oxidase was associated with translocation of cytosolic p47-phox and p67-phox to the plasma membrane as well as redistribution of p47-phox to the Triton-insoluble cytoskeleton. Tetradecanoylphorbol Acetate 51-54 neutrophil cytosolic factor 2 Homo sapiens 190-198 26116564-12 2015 TPA-induced induction of MMP-7 expression was suppressed by AP-1, NF-kappaB, and MAPK (ERK, p38, and JNK) inhibitors, whereas TPA-induced expression of NOX2 and its regulators, p47phox and p67phox, was blocked by p38 and NF-kappaB inhibitors. Tetradecanoylphorbol Acetate 0-3 neutrophil cytosolic factor 2 Homo sapiens 189-196 1985107-2 1991 Two of the cytosolic NADPH oxidase components, p47-phox and p67-phox, translocate to the plasma membrane in normal neutrophils stimulated with phorbol myristate acetate (PMA). Tetradecanoylphorbol Acetate 143-168 neutrophil cytosolic factor 2 Homo sapiens 60-68 1985107-2 1991 Two of the cytosolic NADPH oxidase components, p47-phox and p67-phox, translocate to the plasma membrane in normal neutrophils stimulated with phorbol myristate acetate (PMA). Tetradecanoylphorbol Acetate 170-173 neutrophil cytosolic factor 2 Homo sapiens 60-68 26116564-12 2015 TPA-induced induction of MMP-7 expression was suppressed by AP-1, NF-kappaB, and MAPK (ERK, p38, and JNK) inhibitors, whereas TPA-induced expression of NOX2 and its regulators, p47phox and p67phox, was blocked by p38 and NF-kappaB inhibitors. Tetradecanoylphorbol Acetate 126-129 neutrophil cytosolic factor 2 Homo sapiens 189-196 21784060-3 2011 In this study, we show that p67phox is constitutively phosphorylated in resting human neutrophils and that neutrophil stimulation with PMA further enhanced this phosphorylation. Tetradecanoylphorbol Acetate 135-138 neutrophil cytosolic factor 2 Homo sapiens 28-35