PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1182705-2 1975 This report presents results of a study on the effects of TPA on epidermal histidase (L-histidine ammonia lyase), an enzyme found in normal epidermis but not in dermis or in mouse squamous cell carcinomas. Tetradecanoylphorbol Acetate 58-61 histidine ammonia lyase Mus musculus 75-84 1182705-4 1975 Topical TPA treatment at doses active in tumor promotion (1.7 to 17.0 nmoles/application) produced dose-dependent decreases in epidermal histidase specific activity at 19 hr posttreatment. Tetradecanoylphorbol Acetate 8-11 histidine ammonia lyase Mus musculus 137-146 1182705-7 1975 The strong promoter TPA produced a greater histidase decrease than did the moderate promoter and mitogen 12,13-didecanoyl phorbol at equimolar dose, while phorbol, a nonpromoter and nonmitogen, produced no effects on histidase. Tetradecanoylphorbol Acetate 20-23 histidine ammonia lyase Mus musculus 43-52 1182705-7 1975 The strong promoter TPA produced a greater histidase decrease than did the moderate promoter and mitogen 12,13-didecanoyl phorbol at equimolar dose, while phorbol, a nonpromoter and nonmitogen, produced no effects on histidase. Tetradecanoylphorbol Acetate 20-23 histidine ammonia lyase Mus musculus 217-226