PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1312489-2	1992	24 h treatment of MDBK cells with TPA resulted in down-regulation of VDR number, with no change in the binding affinity for 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) or approximate molecular weight determined by fast protein liquid chromatography (FPLC).	Tetradecanoylphorbol Acetate	34-37	vitamin D receptor	Bos taurus	69-72	
1312489-5	1992	TPA elicited a significant decrease in membrane-associated protein kinase C (PKC) activity which coincided with the reduction in VDR number and calbindin D-28K.	Tetradecanoylphorbol Acetate	0-3	vitamin D receptor	Bos taurus	129-132	
8106362-10	1994	In addition to the distinct effects of 1,25-(OH)2-D3 and TPA on PKC isozyme patterns, 1,25-(OH)2-D3 up-regulates both the vitamin D receptor and calbindin D-28K, whereas TPA down-regulates the expression of both proteins.	Tetradecanoylphorbol Acetate	170-173	vitamin D receptor	Bos taurus	122-140