PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1312489-2 1992 24 h treatment of MDBK cells with TPA resulted in down-regulation of VDR number, with no change in the binding affinity for 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) or approximate molecular weight determined by fast protein liquid chromatography (FPLC). Tetradecanoylphorbol Acetate 34-37 vitamin D receptor Bos taurus 69-72 1312489-5 1992 TPA elicited a significant decrease in membrane-associated protein kinase C (PKC) activity which coincided with the reduction in VDR number and calbindin D-28K. Tetradecanoylphorbol Acetate 0-3 vitamin D receptor Bos taurus 129-132 8106362-10 1994 In addition to the distinct effects of 1,25-(OH)2-D3 and TPA on PKC isozyme patterns, 1,25-(OH)2-D3 up-regulates both the vitamin D receptor and calbindin D-28K, whereas TPA down-regulates the expression of both proteins. Tetradecanoylphorbol Acetate 170-173 vitamin D receptor Bos taurus 122-140