PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7904711-3 1994 Long-term 10(-7)M PMA treatment of cells neither affected membrane basal GC activity nor ANP-s-GC activity but partially inhibited ATP enhancement of ANP-s-GC. Tetradecanoylphorbol Acetate 18-21 natriuretic peptide A Homo sapiens 150-153 9280203-5 1997 The activation of ANP-C receptor by C-ANP(4-23) (a ring-deleted peptide of ANP) and C-type natriuretic peptide inhibits the mitogen-activated protein kinase activity stimulated by endothelin-3, platelet-derived growth factor and phorbol-12 myristate 13-acetate. Tetradecanoylphorbol Acetate 229-260 natriuretic peptide A Homo sapiens 18-21 9280203-5 1997 The activation of ANP-C receptor by C-ANP(4-23) (a ring-deleted peptide of ANP) and C-type natriuretic peptide inhibits the mitogen-activated protein kinase activity stimulated by endothelin-3, platelet-derived growth factor and phorbol-12 myristate 13-acetate. Tetradecanoylphorbol Acetate 229-260 natriuretic peptide A Homo sapiens 38-41 9280203-5 1997 The activation of ANP-C receptor by C-ANP(4-23) (a ring-deleted peptide of ANP) and C-type natriuretic peptide inhibits the mitogen-activated protein kinase activity stimulated by endothelin-3, platelet-derived growth factor and phorbol-12 myristate 13-acetate. Tetradecanoylphorbol Acetate 229-260 natriuretic peptide A Homo sapiens 38-41 7904711-7 1994 The three- to four-fold ATP enhancement of cell membrane ANP-s-GC was not blocked by 12-hour preincubation of cells with 150 ng/mL PT but was completely blocked if 2-x-10(-7)M PMA was then added for 20 minutes, indicating that acute activation of PKC by PMA does not require a functional "G-type" protein. Tetradecanoylphorbol Acetate 176-179 natriuretic peptide A Homo sapiens 57-60 8507443-4 1993 This same TPA response element appears to be responsible for induction of hANP gene promoter activity by the phorbol ester TPA. Tetradecanoylphorbol Acetate 10-13 natriuretic peptide A Homo sapiens 74-78 8232274-8 1993 In addition, we show that like the ANF-R1A, the ANF-R1C guanylyl cyclase activity can be regulated by phosphorylation since preincubation with TPA or FKL attenuates the subsequent stimulation by CNP in cultured cells. Tetradecanoylphorbol Acetate 143-146 natriuretic peptide A Homo sapiens 35-38 8232274-8 1993 In addition, we show that like the ANF-R1A, the ANF-R1C guanylyl cyclase activity can be regulated by phosphorylation since preincubation with TPA or FKL attenuates the subsequent stimulation by CNP in cultured cells. Tetradecanoylphorbol Acetate 143-146 natriuretic peptide A Homo sapiens 48-51 8507443-4 1993 This same TPA response element appears to be responsible for induction of hANP gene promoter activity by the phorbol ester TPA. Tetradecanoylphorbol Acetate 123-126 natriuretic peptide A Homo sapiens 74-78 1648714-5 1991 Phorbol 12-myristate 13-acetate (PMA), a protein kinase C (PKC) activator, and A23187 and its 4-bromo derivative, calcium ionophores, inhibited ANF-s-cGMP in a dose-dependent manner. Tetradecanoylphorbol Acetate 0-31 natriuretic peptide A Homo sapiens 144-147 1314851-5 1992 Phorbol 12-myristate 13-acetate, opsonized zymosan, or FMLP could all be used as triggering stimuli to demonstrate the priming of PMN activation by ANP. Tetradecanoylphorbol Acetate 0-31 natriuretic peptide A Homo sapiens 148-151 1648714-5 1991 Phorbol 12-myristate 13-acetate (PMA), a protein kinase C (PKC) activator, and A23187 and its 4-bromo derivative, calcium ionophores, inhibited ANF-s-cGMP in a dose-dependent manner. Tetradecanoylphorbol Acetate 33-36 natriuretic peptide A Homo sapiens 144-147 1648714-7 1991 Thirty-six hour preincubation with PMA, a procedure used to down-regulate PKC, abolished acute PMA inhibition of ANF-s-cGMP without having an effect on ANF-s-cGMP or on 4-bromo-A23187 inhibition thereof. Tetradecanoylphorbol Acetate 35-38 natriuretic peptide A Homo sapiens 113-116 1671790-1 1991 In the present study, we investigated the effects of calmodulin, adenosine 5"-triphosphate (ATP) and pertussis toxin (PT) on phorbol ester (PMA) (a protein kinase C activator) induced inhibition of ANF-stimulated cyclic GMP formation in cells from the human renal cell line, SK-NEP-1. Tetradecanoylphorbol Acetate 140-143 natriuretic peptide A Homo sapiens 198-201