PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10545022-0	1999	TPA-enhanced motility and invasion in a highly metastatic variant (L-10) of human rectal adenocarcinoma cell line RCM-1: selective role of PKC-alpha and its inhibition by a combination of PDBu-induced PKC downregulation and antisense oligonucleotides treatment.	Tetradecanoylphorbol Acetate	0-3	immunoglobulin kappa variable 3-7 (non-functional)	Homo sapiens	67-71	
10545022-1	1999	We previously found that 12-O-tetradecanoylphorbol-13-acetate (TPA)-enhanced invasiveness was associated with augmentation of cell motility but not that of metalloproteinase activity in a highly metastatic variant (L-10) of the human colon adenocarcinoma cell line RCM-1 and that this enhancement was possibly mediated by protein kinase C (PKC).	Tetradecanoylphorbol Acetate	63-66	immunoglobulin kappa variable 3-7 (non-functional)	Homo sapiens	215-219	
10545022-2	1999	In this study, we first intended to determine the specific isoforms of PKC involved in this TPA-enhanced L-10 cell motility that leads to invasion, and then investigated the way to inhibit the enhanced motility and invasion by using antisense oligodeoxynucleotides (ODN) targeting the isoform.	Tetradecanoylphorbol Acetate	92-95	immunoglobulin kappa variable 3-7 (non-functional)	Homo sapiens	105-109	
10545022-3	1999	An activator of conventional PKC isoforms (cPKC), thymeleatoxin, enhanced L-10 cell motility and invasion like TPA, and an inhibitor of cPKC, Go-6976, efficiently inhibited TPA-enhanced motility and invasion.	Tetradecanoylphorbol Acetate	111-114	immunoglobulin kappa variable 3-7 (non-functional)	Homo sapiens	74-78