PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2547991-0	1989	Loss of responsiveness of an AP1-related factor, PEBP1, to 12-O-tetradecanoylphorbol-13-acetate after transformation of NIH 3T3 cells by the Ha-ras oncogene.	Tetradecanoylphorbol Acetate	59-95	phosphatidylethanolamine binding protein 1	Mus musculus	49-54	
18400024-2	2008	MATERIALS AND METHODS: Effect of PBP pre-treatments on 12-O-tetradecanoylphorbol-13-acetate (TPA) promoted skin papillomas was studied in 7,12-dimethylbenz(a)anthracene initiated mice over 40 weeks.	Tetradecanoylphorbol Acetate	55-91	phosphatidylethanolamine binding protein 1	Mus musculus	33-36	
22841871-3	2012	In this study, mechanisms of PBP-mediated antipromoting effects were investigated in a mouse model employing the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA).	Tetradecanoylphorbol Acetate	128-164	phosphatidylethanolamine binding protein 1	Mus musculus	29-32	
22841871-3	2012	In this study, mechanisms of PBP-mediated antipromoting effects were investigated in a mouse model employing the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA).	Tetradecanoylphorbol Acetate	166-169	phosphatidylethanolamine binding protein 1	Mus musculus	29-32	
22841871-7	2012	Complementary confocal microscopic evaluation showed a decrease in TPA-induced PKCalpha fluorescence in PBP-3-pretreated membranes, whereas pretreatment with PBP-5 did not show a similar decrease.	Tetradecanoylphorbol Acetate	67-70	phosphatidylethanolamine binding protein 1	Mus musculus	104-107	
22841871-8	2012	Based on the experiments with specific enzyme inhibitors and phosphospecific antibodies, both PBP-3 and PBP-5 were observed to decrease TPA-induced level and/or activity of phosphatidylinositol 3-kinase (PI3K) and AKT1 (pS473).	Tetradecanoylphorbol Acetate	136-139	phosphatidylethanolamine binding protein 1	Mus musculus	94-97	
22841871-8	2012	Based on the experiments with specific enzyme inhibitors and phosphospecific antibodies, both PBP-3 and PBP-5 were observed to decrease TPA-induced level and/or activity of phosphatidylinositol 3-kinase (PI3K) and AKT1 (pS473).	Tetradecanoylphorbol Acetate	136-139	phosphatidylethanolamine binding protein 1	Mus musculus	104-107	
22841871-10	2012	Altogether, PBP-mediated decrease in TPA-induced PKC phosphorylation correlated well with decreased TPA-induced NF-kappaB phosphorylation and downstream target proteins associated with proliferation, apoptosis, and inflammation in mouse skin.	Tetradecanoylphorbol Acetate	37-40	phosphatidylethanolamine binding protein 1	Mus musculus	12-15	
22841871-10	2012	Altogether, PBP-mediated decrease in TPA-induced PKC phosphorylation correlated well with decreased TPA-induced NF-kappaB phosphorylation and downstream target proteins associated with proliferation, apoptosis, and inflammation in mouse skin.	Tetradecanoylphorbol Acetate	100-103	phosphatidylethanolamine binding protein 1	Mus musculus	12-15	
18400024-2	2008	MATERIALS AND METHODS: Effect of PBP pre-treatments on 12-O-tetradecanoylphorbol-13-acetate (TPA) promoted skin papillomas was studied in 7,12-dimethylbenz(a)anthracene initiated mice over 40 weeks.	Tetradecanoylphorbol Acetate	93-96	phosphatidylethanolamine binding protein 1	Mus musculus	33-36	
18400024-6	2008	Most PBP fractions decreased TPA-induced cell proliferation by decreasing activation of signalling kinases (c-Jun N-terminal protein kinase, extracellular signal-regulated protein kinase, p38 protein kinase and Akt), transcription factors (activator protein-1 and nuclear factor kappa B) and inflammatory protein (cyclooxygenase 2).	Tetradecanoylphorbol Acetate	29-32	phosphatidylethanolamine binding protein 1	Mus musculus	5-8	
18400024-7	2008	TPA-induced epidermal cell apoptosis was also decreased by pre-treatment with most PBP fractions.	Tetradecanoylphorbol Acetate	0-3	phosphatidylethanolamine binding protein 1	Mus musculus	83-86	
18400024-8	2008	Higher levels of p53 and p21 in skin cells pre-treated with PBP fractions followed by TPA treatment as compared to only TPA-treated animals suggested possible activation of a cell cycle checkpoint.	Tetradecanoylphorbol Acetate	120-123	phosphatidylethanolamine binding protein 1	Mus musculus	60-63	
18400024-10	2008	In conclusion, the protective effects of PBP fractions could be attributed to inhibition of TPA-induced cellular proliferation.	Tetradecanoylphorbol Acetate	92-95	phosphatidylethanolamine binding protein 1	Mus musculus	41-44