PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16995904-2 2006 OBJECTIVES: We studied Galphaq promoter activity using luciferase reporter gene assays in human erythroleukemia (HEL) cells treated with phorbol 12-myristate 13-acetate (PMA) for 24 h to induce megakaryocytic transformation. Tetradecanoylphorbol Acetate 137-168 G protein subunit alpha q Homo sapiens 23-30 18989526-0 2008 Phorbol 12-myristate 13-acetate (PMA) responsive sequence in Galphaq promoter during megakaryocytic differentiation. Tetradecanoylphorbol Acetate 0-31 G protein subunit alpha q Homo sapiens 61-68 18989526-0 2008 Phorbol 12-myristate 13-acetate (PMA) responsive sequence in Galphaq promoter during megakaryocytic differentiation. Tetradecanoylphorbol Acetate 33-36 G protein subunit alpha q Homo sapiens 61-68 18989526-3 2008 We have reported that Galphaq is upregulated during phorbol 12-myristate 13-acetate (PMA)-induced megakaryocytic transformation of human erythroleukemia (HEL) cells and regulated by EGR-1, an early growth transcription factor. Tetradecanoylphorbol Acetate 52-83 G protein subunit alpha q Homo sapiens 22-29 18989526-3 2008 We have reported that Galphaq is upregulated during phorbol 12-myristate 13-acetate (PMA)-induced megakaryocytic transformation of human erythroleukemia (HEL) cells and regulated by EGR-1, an early growth transcription factor. Tetradecanoylphorbol Acetate 85-88 G protein subunit alpha q Homo sapiens 22-29 18989526-6 2008 In luciferase reporter gene studies in HEL cells, Galphaq 5" upstream promoter sequence -1042/-1 showed an about four-fold increased activity in PMA-treated compared to untreated cells. Tetradecanoylphorbol Acetate 145-148 G protein subunit alpha q Homo sapiens 50-57 18989526-8 2008 Gel-shift studies on Galphaq probe (-1042/-1012 bp) revealed binding of EGR-1 with PMA-treated but not untreated nuclear extracts, and this was dependent on the sequence -1042/-1037. Tetradecanoylphorbol Acetate 83-86 G protein subunit alpha q Homo sapiens 21-28 16995904-2 2006 OBJECTIVES: We studied Galphaq promoter activity using luciferase reporter gene assays in human erythroleukemia (HEL) cells treated with phorbol 12-myristate 13-acetate (PMA) for 24 h to induce megakaryocytic transformation. Tetradecanoylphorbol Acetate 170-173 G protein subunit alpha q Homo sapiens 23-30 9575800-7 1998 However, protein kinase C (PKC) levels were downregulated in TPA-treated cells but not in alpha qQ209L-expressing cells, suggesting that the regulation of PKC by G alpha q may be different from regulation by TPA. Tetradecanoylphorbol Acetate 61-64 G protein subunit alpha q Homo sapiens 162-171