PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28186503-4 2017 We found that following 12-O-tetradecanoyl-phorbol-13-acetate (TPA) topical treatment, DLX3 expression is significantly upregulated in the epidermis and keratinocytes from mice overexpressing PKCalpha by transgenic targeting (K5-PKCalpha), resulting in cell cycle block and terminal differentiation. Tetradecanoylphorbol Acetate 24-61 distal-less homeobox 3 Mus musculus 87-91 28186503-4 2017 We found that following 12-O-tetradecanoyl-phorbol-13-acetate (TPA) topical treatment, DLX3 expression is significantly upregulated in the epidermis and keratinocytes from mice overexpressing PKCalpha by transgenic targeting (K5-PKCalpha), resulting in cell cycle block and terminal differentiation. Tetradecanoylphorbol Acetate 63-66 distal-less homeobox 3 Mus musculus 87-91 28186503-6 2017 Of particular significance, transcriptional activation of epidermal barrier, antimicrobial peptide and cytokine genes is significantly increased in DLX3cKO skin and further increased by TPA-dependent PKC activation. Tetradecanoylphorbol Acetate 186-189 distal-less homeobox 3 Mus musculus 148-155