PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16368122-5	2006	Arsenic/TPA treatment resulted in increased expression of alpha-fetoprotein, k-ras, c-myc, estrogen receptor-alpha, cyclin D1, cdk2na, plasminogen activator inhibitor-1, cytokeratin-8, cytokeratin-18, glutathione S-transferases and insulin-like growth factor binding proteins in liver and liver tumors from both male and female mice.	Tetradecanoylphorbol Acetate	8-11	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	77-82	
3409475-6	1988	In contrast, another single-step, high dose MCA transformant (MCACl#16/39) known to contain an activated c-Ki-ras gene shows TPA-independent focus formation in mixed culture with C3H/10T1/2 cells, anchorage independence and tumorigenicity.	Tetradecanoylphorbol Acetate	125-128	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	105-113	
12151388-12	2002	Furthermore, K-Ras, the isoform previously shown to bind to calmodulin, is the only one activated by TPA when calmodulin is inhibited.	Tetradecanoylphorbol Acetate	101-104	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	13-18	
12151388-14	2002	In vitro experiments showed that the phosphorylation of K-Ras by PKC was inhibited by calmodulin, suggesting that calmodulin-dependent modulation of K-Ras phosphorylation by PKC could be the mechanism underlying K-Ras activation in fibroblasts treated with TPA plus W13.	Tetradecanoylphorbol Acetate	257-260	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	56-61	
12151388-14	2002	In vitro experiments showed that the phosphorylation of K-Ras by PKC was inhibited by calmodulin, suggesting that calmodulin-dependent modulation of K-Ras phosphorylation by PKC could be the mechanism underlying K-Ras activation in fibroblasts treated with TPA plus W13.	Tetradecanoylphorbol Acetate	257-260	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	149-154	
12151388-14	2002	In vitro experiments showed that the phosphorylation of K-Ras by PKC was inhibited by calmodulin, suggesting that calmodulin-dependent modulation of K-Ras phosphorylation by PKC could be the mechanism underlying K-Ras activation in fibroblasts treated with TPA plus W13.	Tetradecanoylphorbol Acetate	257-260	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	149-154	
9819387-8	1998	The C1 domain could also confer phorbol myristate acetate-regulated transforming activity on a prenylation-defective mutant of K-Ras.	Tetradecanoylphorbol Acetate	32-57	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	127-132