PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27327144-12	2017	Exposure to PMA/ionomycin following dextramer exposure resulted in a homogeneous NFAT activation in both the dextramer-positive but NFAT1 nonresponsive CAST and non-CAST cells.	Tetradecanoylphorbol Acetate	12-15	nuclear factor of activated T cells 2	Homo sapiens	132-137	
23105117-5	2012	VRK2 increases NFAT1-dependent transcription by phosphorylation, and this effect is only detected following cell phorbol 12-myristate 13-acetate and ionomycin stimulation and calcineurin activation.	Tetradecanoylphorbol Acetate	113-144	nuclear factor of activated T cells 2	Homo sapiens	15-20	
15117942-6	2004	Furthermore, we found that treatment with both ionomycin and phorbol 12-myristate 13-acetate ensured efficient nuclear anchorage with the recruitment of NFAT1 into the SUMO-1 bodies, whereas treatment with ionomycin alone induced nuclear translocation of NFAT1 but not recruitment into the SUMO-1 bodies.	Tetradecanoylphorbol Acetate	61-92	nuclear factor of activated T cells 2	Homo sapiens	153-158	
19309550-7	2009	Immunofluorescence data show that ST1959 inhibits the nuclear residency of NFAT1 in both Jurkat and human peripheral blood mononuclear cells activated with PMA/ionomycin.	Tetradecanoylphorbol Acetate	156-159	nuclear factor of activated T cells 2	Homo sapiens	75-80	
15117942-6	2004	Furthermore, we found that treatment with both ionomycin and phorbol 12-myristate 13-acetate ensured efficient nuclear anchorage with the recruitment of NFAT1 into the SUMO-1 bodies, whereas treatment with ionomycin alone induced nuclear translocation of NFAT1 but not recruitment into the SUMO-1 bodies.	Tetradecanoylphorbol Acetate	61-92	nuclear factor of activated T cells 2	Homo sapiens	255-260	
15117942-7	2004	Our results suggest that the recruitment of NFAT1 into SUMO-1 bodies may be required for the progressive transcriptional activity of NFAT1 upon co-stimulation with ionomycin and phorbol 12-myristate 13-acetate, whereas anergic transcription stimulated by ionomycin alone may occur without recruitment into the SUMO-1 bodies.	Tetradecanoylphorbol Acetate	178-209	nuclear factor of activated T cells 2	Homo sapiens	44-49	
15117942-7	2004	Our results suggest that the recruitment of NFAT1 into SUMO-1 bodies may be required for the progressive transcriptional activity of NFAT1 upon co-stimulation with ionomycin and phorbol 12-myristate 13-acetate, whereas anergic transcription stimulated by ionomycin alone may occur without recruitment into the SUMO-1 bodies.	Tetradecanoylphorbol Acetate	178-209	nuclear factor of activated T cells 2	Homo sapiens	133-138	
10940935-0	2000	Requirement for integration of phorbol 12-myristate 13-acetate and calcium pathways is preserved in the transactivation domain of NFAT1.	Tetradecanoylphorbol Acetate	31-62	nuclear factor of activated T cells 2	Homo sapiens	130-135	
11982754-11	2002	Agonists that induce keratinocyte differentiation, specifically 12-0-tetradecanoyl-phorbol-13-acetate (TPA) plus ionomycin, TPA, and raised extracellular calcium, induced nuclear translocation of NFAT1 and calcineurin in keratinocytes that was inhibited by pretreatment with cyclosporin A or tacrolimus.	Tetradecanoylphorbol Acetate	103-106	nuclear factor of activated T cells 2	Homo sapiens	196-201	
11982754-11	2002	Agonists that induce keratinocyte differentiation, specifically 12-0-tetradecanoyl-phorbol-13-acetate (TPA) plus ionomycin, TPA, and raised extracellular calcium, induced nuclear translocation of NFAT1 and calcineurin in keratinocytes that was inhibited by pretreatment with cyclosporin A or tacrolimus.	Tetradecanoylphorbol Acetate	124-127	nuclear factor of activated T cells 2	Homo sapiens	196-201	
11856352-7	2002	All-trans-RA blocked translocation of NFATp from the cytosol into the nucleus, which was induced by PMA/ionomycin treatment in HeLa cells transfected with a Flag-tagged NFATp.	Tetradecanoylphorbol Acetate	100-103	nuclear factor of activated T cells 2	Homo sapiens	38-43	
11856352-7	2002	All-trans-RA blocked translocation of NFATp from the cytosol into the nucleus, which was induced by PMA/ionomycin treatment in HeLa cells transfected with a Flag-tagged NFATp.	Tetradecanoylphorbol Acetate	100-103	nuclear factor of activated T cells 2	Homo sapiens	169-174	
8668212-5	1996	Deactivation of NFAT1 is facilitated by phorbol 12-myristate 13-acetate and inhibitors of capacitative calcium entry and most likely reflects the slow return of intracellular free calcium concentrations towards resting levels.	Tetradecanoylphorbol Acetate	40-71	nuclear factor of activated T cells 2	Homo sapiens	16-21	
10590260-9	1999	We investigated the functional significance of NFATp binding to CK-1 by overexpressing the protein in Jurkat T cells and found that NFATp cannot activate the CD28RR alone but can cooperate with signals generated by phorbol 12-myristate 13-acetate/calcium ionophore.	Tetradecanoylphorbol Acetate	215-246	nuclear factor of activated T cells 2	Homo sapiens	47-52	
8668213-6	1996	When expressed in COS cells, however, NFAT1 is capable of transactivation, but it is not regulated correctly: its subcellular localization and transcriptional function are not affected by stimulation of the COS cells with ionomycin and phorbol 12-myristate 13-acetate.	Tetradecanoylphorbol Acetate	236-267	nuclear factor of activated T cells 2	Homo sapiens	38-43	
8668213-4	1996	Transactivation by recombinant NFAT1 in Jurkat T cells requires dual stimulation with ionomycin and phorbol 12-myristate 13-acetate; this activity is potentiated by coexpression of constitutively active calcineurin and is inhibited by CsA.	Tetradecanoylphorbol Acetate	100-131	nuclear factor of activated T cells 2	Homo sapiens	31-36