PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9195048-1 1997 The induction of JE/MCP-1 gene by TPA was transcriptionally suppressed by antioxidants such as pyrrolidine dithiocarbamate (PDTC) or trimethylthiourea (TMTU) in Balb 3T3 cells, whereas that of other early response genes, c-fos or egr-1, was not affected by these agents. Tetradecanoylphorbol Acetate 34-37 early growth response 1 Mus musculus 230-235 8848429-8 1996 Inhibition of protein kinase C activity by pretreatment with 1 microM chelerythrine chloride or by prolonged stimulation with 50 ng/ml tetradecanoyl phorbol acetate (TPA) attenuated the induction of Egr-1 mRNA by 2 microM PGE2. Tetradecanoylphorbol Acetate 135-164 early growth response 1 Mus musculus 199-204 9012782-5 1997 The egr-1 gene elevation was not blocked by prior exposure to indomethacin, saralasin, Rp-cAMP, A23187, and colchicine, and it was blocked partially by cytochalasin D, H-7, and prolonged exposure to TPA. Tetradecanoylphorbol Acetate 199-202 early growth response 1 Mus musculus 4-9 8621772-3 1996 Urea inducibility of Egr-1 expression was protein kinase C (PKC)-dependent because staurosporine and calphostin C abrogated the urea effect, and down-regulation of PHC through chronic TPa treatment inhibited both urea-inducible Egr-1 protein expression and gene transcription. Tetradecanoylphorbol Acetate 184-187 early growth response 1 Mus musculus 21-26 8621772-5 1996 Importantly, urea-inducible Egr-1 expression was strongly genistein-sensitive, to a much greater extent than the comparable TPA-inducible Egr-1 expression. Tetradecanoylphorbol Acetate 124-127 early growth response 1 Mus musculus 138-143 8848429-8 1996 Inhibition of protein kinase C activity by pretreatment with 1 microM chelerythrine chloride or by prolonged stimulation with 50 ng/ml tetradecanoyl phorbol acetate (TPA) attenuated the induction of Egr-1 mRNA by 2 microM PGE2. Tetradecanoylphorbol Acetate 166-169 early growth response 1 Mus musculus 199-204 7768965-1 1995 As a part of a series of investigations on the functions of TIS21 and TIS1 genes, we measured in vivo 12-O-tetradecanoylphorbol-13-acetate (TPA) inducibility of primary response genes (TIS21, TIS8 and TIS1) in the Balb/c mice and the changes of TIS gene expression in thymic carcinoma tissues and A549 and NCIH69 human lung cancer cell lines. Tetradecanoylphorbol Acetate 102-138 early growth response 1 Mus musculus 192-196 8581878-4 1995 Inhibition of protein kinase C activity by pretreatment with 1 microM chelerythrine chloride or by prolonged stimulation with 50 ng/ml tetradecanoyl phorbol acetate (TPA) partially diminished the induction of Egr-1 by EGF. Tetradecanoylphorbol Acetate 135-164 early growth response 1 Mus musculus 209-214 8581878-4 1995 Inhibition of protein kinase C activity by pretreatment with 1 microM chelerythrine chloride or by prolonged stimulation with 50 ng/ml tetradecanoyl phorbol acetate (TPA) partially diminished the induction of Egr-1 by EGF. Tetradecanoylphorbol Acetate 166-169 early growth response 1 Mus musculus 209-214 7961634-8 1994 In contrast, inhibition of protein kinase C by calphostin C and chelerythrine or down-regulation with phorbol 12-myristate 13-acetate drastically reduces PGE2 and arachidonic acid-induced c-fos and Egr-1 mRNA levels. Tetradecanoylphorbol Acetate 102-133 early growth response 1 Mus musculus 198-203 2677677-5 1989 When GM-CSF-deprived 32D clone 3 cells were exposed to GM-CSF or to TPA, four TIS mRNAs (TIS7, TIS8, TIS10, and TIS11) were rapidly and transiently induced. Tetradecanoylphorbol Acetate 68-71 early growth response 1 Mus musculus 95-99 2513479-1 1989 The zif268 gene, which encodes a protein with three typical zinc finger sequences, is induced in mouse 3T3 cells by serum, phorbol 12-myristate 13-acetate platelet-derived growth factor, and fibroblast growth factor. Tetradecanoylphorbol Acetate 123-154 early growth response 1 Mus musculus 4-10 7510248-4 1994 In cells pretreated with 12-O-tetradecanoylphorbol 13-acetate, induction of c-fos by hypergravity was almost completely abolished, whereas that of egr-1 was not affected. Tetradecanoylphorbol Acetate 25-61 early growth response 1 Mus musculus 147-152 8426742-8 1993 The serum induction of c-fos and junD as well as the serum and TPA (12-O-tetradecanoylphorbol-13-acetate) induction of junB and egr-1 are almost completely abolished. Tetradecanoylphorbol Acetate 63-66 early growth response 1 Mus musculus 128-133 8426742-8 1993 The serum induction of c-fos and junD as well as the serum and TPA (12-O-tetradecanoylphorbol-13-acetate) induction of junB and egr-1 are almost completely abolished. Tetradecanoylphorbol Acetate 68-104 early growth response 1 Mus musculus 128-133 1584230-7 1992 Furthermore, we found Egr-1 expression could be achieved by direct activation of protein kinase C (PKC) by phorbol 12-myristate 13-acetate (PMA) circumventing the classical sIg activated phosphatidylinositol signal transduction pathway. Tetradecanoylphorbol Acetate 107-138 early growth response 1 Mus musculus 22-27 1584230-7 1992 Furthermore, we found Egr-1 expression could be achieved by direct activation of protein kinase C (PKC) by phorbol 12-myristate 13-acetate (PMA) circumventing the classical sIg activated phosphatidylinositol signal transduction pathway. Tetradecanoylphorbol Acetate 140-143 early growth response 1 Mus musculus 22-27 2005129-10 1991 Endogenous protein kinase C activity in macrophages was depleted by treatment with 12-O-tetradecanoylphorbol-13-acetate for 24 h. GM-CSF increased Egr-1 mRNA in protein kinase C-depleted macrophages, whereas the stimulatory effect of 12-O-tetradecanoylphorbol-13-acetate on Egr-1 was blocked. Tetradecanoylphorbol Acetate 234-270 early growth response 1 Mus musculus 147-152 2500119-0 1989 Indomethacin shifts the peak of c-fos, egr-1, and c-myc gene expression in confluent fibroblasts induced by phorbol myristate acetate. Tetradecanoylphorbol Acetate 108-133 early growth response 1 Mus musculus 39-44 16515541-0 2006 Up-regulation of tyrosine hydroxylase gene transcription by tetradecanoylphorbol acetate is mediated by the transcription factors Ets-like protein-1 (Elk-1) and Egr-1. Tetradecanoylphorbol Acetate 60-88 early growth response 1 Mus musculus 161-166 16515541-7 2006 Expression of dominant-negative mutants of Elk-1 or Egr-1 impaired TPA-induced stimulation of a tyrosine hydroxylase promoter/reporter gene transcription. Tetradecanoylphorbol Acetate 67-70 early growth response 1 Mus musculus 52-57 10747287-5 2000 After a single topical treatment with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) to SENCAR mouse skin, Egr-1 mRNA was induced, and maximal induction was observed at 2 h in both epidermis and dermis. Tetradecanoylphorbol Acetate 57-93 early growth response 1 Mus musculus 122-127 10747287-5 2000 After a single topical treatment with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) to SENCAR mouse skin, Egr-1 mRNA was induced, and maximal induction was observed at 2 h in both epidermis and dermis. Tetradecanoylphorbol Acetate 95-98 early growth response 1 Mus musculus 122-127 10747287-6 2000 Induction of Egr-1 mRNA by TPA was inhibited by fluocinolone acetonide, a potent inhibitor of tumor promotion by TPA. Tetradecanoylphorbol Acetate 27-30 early growth response 1 Mus musculus 13-18 10747287-6 2000 Induction of Egr-1 mRNA by TPA was inhibited by fluocinolone acetonide, a potent inhibitor of tumor promotion by TPA. Tetradecanoylphorbol Acetate 113-116 early growth response 1 Mus musculus 13-18 26100520-7 2015 Furthermore, NF-kappaB, Egr-1, and AP-1 DNA binding activities after TPA treatment were dramatically decreased by the combination of ursolic acid + resveratrol. Tetradecanoylphorbol Acetate 69-72 early growth response 1 Mus musculus 24-29