PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12755693-8 2003 Moreover, the PMA dependent decrease of the mature enzyme form is specific for TACE, as the amount of mature ADAM10 was unaffected in PMA-treated HEK293 and SH-SY5Y cells. Tetradecanoylphorbol Acetate 14-17 ADAM metallopeptidase domain 10 Homo sapiens 109-115 25652588-4 2015 We show here that activation or overexpression of constitutively active merlin or downregulation of ERMs inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced [as well as serum, hepatocyte growth factor (HGF), or platelet-derived growth factor (PDGF)] CD44 cleavage by the metalloprotease ADAM10, whereas overexpressed ERM proteins promoted cleavage. Tetradecanoylphorbol Acetate 115-151 ADAM metallopeptidase domain 10 Homo sapiens 296-302 25652588-4 2015 We show here that activation or overexpression of constitutively active merlin or downregulation of ERMs inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced [as well as serum, hepatocyte growth factor (HGF), or platelet-derived growth factor (PDGF)] CD44 cleavage by the metalloprotease ADAM10, whereas overexpressed ERM proteins promoted cleavage. Tetradecanoylphorbol Acetate 153-156 ADAM metallopeptidase domain 10 Homo sapiens 296-302 21288900-8 2011 Using protease inhibitors, ionomycin and phorbol myristate acetate stimulation, small interfering RNA knockdown, and site-directed mutagenesis, we found that ADAM10 was primarily responsible for shedding corin in its juxtamembrane region to release the ~180-kDa fragment, corresponding to the near-entire extracellular region. Tetradecanoylphorbol Acetate 41-66 ADAM metallopeptidase domain 10 Homo sapiens 158-164 27599715-2 2016 We here report that stimulation of lung epithelial A549 tumor cells with phorbol-12-myristate-13-acetate (PMA) leads to the downregulation of the surface expressed mature form of ADAM17 without affecting ADAM10 expression. Tetradecanoylphorbol Acetate 73-104 ADAM metallopeptidase domain 10 Homo sapiens 204-210 27599715-2 2016 We here report that stimulation of lung epithelial A549 tumor cells with phorbol-12-myristate-13-acetate (PMA) leads to the downregulation of the surface expressed mature form of ADAM17 without affecting ADAM10 expression. Tetradecanoylphorbol Acetate 106-109 ADAM metallopeptidase domain 10 Homo sapiens 204-210