PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9685416-6	1998	Hence, the pervanadate and 12-O-tetradecanoylphorbol-13-acetate-induced proteolytic cleavage of ErbB-4 seem to proceed by different mechanisms, although both require metalloprotease activity.	Tetradecanoylphorbol Acetate	27-63	erb-b2 receptor tyrosine kinase 4	Homo sapiens	96-102	
16061658-5	2005	Stimulation of ErbB-4-expressing cells with 12-O-tetradecanoylphorbol-13-acetate (TPA) results in the proteolytic cleavage of its cytoplasmic domain and translocation of this domain to the nucleus.	Tetradecanoylphorbol Acetate	44-80	erb-b2 receptor tyrosine kinase 4	Homo sapiens	15-21	
16061658-5	2005	Stimulation of ErbB-4-expressing cells with 12-O-tetradecanoylphorbol-13-acetate (TPA) results in the proteolytic cleavage of its cytoplasmic domain and translocation of this domain to the nucleus.	Tetradecanoylphorbol Acetate	82-85	erb-b2 receptor tyrosine kinase 4	Homo sapiens	15-21	
16061658-7	2005	Coexpression of WWOX and ErbB-4 in HeLa cells followed by treatment with TPA results in the retention of ErbB-4 in the cytoplasm.	Tetradecanoylphorbol Acetate	73-76	erb-b2 receptor tyrosine kinase 4	Homo sapiens	105-111	
12807903-1	2003	The ErbB-4 receptor protein-tyrosine kinase is proteolytically processed by membrane proteases in response to the ligand or 12-O-tetradecanoylphorbol-13-acetate stimulation resulting in the cytoplasmic fragment translocating to the cell nucleus.	Tetradecanoylphorbol Acetate	124-160	erb-b2 receptor tyrosine kinase 4	Homo sapiens	4-10	
11679632-2	2001	After binding of its ligand heregulin (HRG) or activation of protein kinase C (PKC) by 12-O-tetradecanoylphorbol-13-acetate (TPA), the ErbB-4 ectodomain is cleaved by a metalloprotease.	Tetradecanoylphorbol Acetate	87-123	erb-b2 receptor tyrosine kinase 4	Homo sapiens	135-141	
10744726-5	2000	Moreover, we show that the sequence specific to the HER4 JM-a juxtamembrane region is sufficient to confer susceptibility to phorbol 12-myristate 13-acetate-induced cleavage of the HER2 receptor.	Tetradecanoylphorbol Acetate	125-156	erb-b2 receptor tyrosine kinase 4	Homo sapiens	52-56	
31053301-3	2019	TPA as an activator of the ERK pathway markedly induced ErbB4 phosphorylation at Thr-674, the conserved common feedback site in the intracellular JM domain, which resulted in the downregulation of tyrosine autophosphorylation.	Tetradecanoylphorbol Acetate	0-3	erb-b2 receptor tyrosine kinase 4	Homo sapiens	56-61	
12869563-7	2003	When the m80 ErbB-4 fragment is generated by cell treatment with heregulin or 12-O-tetradecanoylphorbol-13-acetate, the fragment associates with intact ErbB-2.	Tetradecanoylphorbol Acetate	78-114	erb-b2 receptor tyrosine kinase 4	Homo sapiens	13-19