PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21292826-6 2011 The SRF site alone is sufficient for induction by GnRH, whereas induction by 12-tetradecanoylphorbol-13-acetate (TPA) requires both the ELK1 and SRF sites. Tetradecanoylphorbol Acetate 113-116 ELK1, member of ETS oncogene family Mus musculus 136-140 22461904-6 2012 The further mechanistic studies showed that JWA deficiency blocked TPA-induced activation of MAPKs and its downstream transcription factor Elk1 both in vitro and in vivo. Tetradecanoylphorbol Acetate 67-70 ELK1, member of ETS oncogene family Mus musculus 139-143 22461904-7 2012 JWA(Delta2/Delta2) mice are resistance to tumorigenesis induced by DMBA/TPA probably through inhibition of transcription factor Elk1 via MAPKs. Tetradecanoylphorbol Acetate 72-75 ELK1, member of ETS oncogene family Mus musculus 128-132 16515541-0 2006 Up-regulation of tyrosine hydroxylase gene transcription by tetradecanoylphorbol acetate is mediated by the transcription factors Ets-like protein-1 (Elk-1) and Egr-1. Tetradecanoylphorbol Acetate 60-88 ELK1, member of ETS oncogene family Mus musculus 130-148 21292826-6 2011 The SRF site alone is sufficient for induction by GnRH, whereas induction by 12-tetradecanoylphorbol-13-acetate (TPA) requires both the ELK1 and SRF sites. Tetradecanoylphorbol Acetate 77-111 ELK1, member of ETS oncogene family Mus musculus 136-140 16515541-0 2006 Up-regulation of tyrosine hydroxylase gene transcription by tetradecanoylphorbol acetate is mediated by the transcription factors Ets-like protein-1 (Elk-1) and Egr-1. Tetradecanoylphorbol Acetate 60-88 ELK1, member of ETS oncogene family Mus musculus 150-155 16515541-3 2006 We have analysed the stimulation of tyrosine hydroxylase gene transcription by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) in noradrenergic locus coeruleus-like CATH.a cells and observed a striking enhancement of the transcriptional activation potential of the ternary complex factor Ets-like protein-1 (Elk-1), a key transcriptional regulator of serum response element-driven gene transcription. Tetradecanoylphorbol Acetate 135-138 ELK1, member of ETS oncogene family Mus musculus 301-319 16515541-3 2006 We have analysed the stimulation of tyrosine hydroxylase gene transcription by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) in noradrenergic locus coeruleus-like CATH.a cells and observed a striking enhancement of the transcriptional activation potential of the ternary complex factor Ets-like protein-1 (Elk-1), a key transcriptional regulator of serum response element-driven gene transcription. Tetradecanoylphorbol Acetate 135-138 ELK1, member of ETS oncogene family Mus musculus 321-326 16515541-7 2006 Expression of dominant-negative mutants of Elk-1 or Egr-1 impaired TPA-induced stimulation of a tyrosine hydroxylase promoter/reporter gene transcription. Tetradecanoylphorbol Acetate 67-70 ELK1, member of ETS oncogene family Mus musculus 43-48 10722731-5 2000 Surprisingly, we observed that expression of N17Ras inhibited the activity and phosphorylation of Elk-1, a physiological substrate of MAP kinases, in response to phorbol myristate acetate. Tetradecanoylphorbol Acetate 162-187 ELK1, member of ETS oncogene family Mus musculus 98-103 11050045-6 2000 Interestingly, Elk-1 activities were further enhanced by the tumor promoter, 12-O-tetradecanoyl phorbol 13-acetate (TPA), but not by hepatocyte mitogens (epidermal growth factor [EGF] and transforming growth factor alpha [TGF-alpha]) in NIH3T3 cells and HepG2 cells expressing HCV core protein. Tetradecanoylphorbol Acetate 77-114 ELK1, member of ETS oncogene family Mus musculus 15-20 11050045-6 2000 Interestingly, Elk-1 activities were further enhanced by the tumor promoter, 12-O-tetradecanoyl phorbol 13-acetate (TPA), but not by hepatocyte mitogens (epidermal growth factor [EGF] and transforming growth factor alpha [TGF-alpha]) in NIH3T3 cells and HepG2 cells expressing HCV core protein. Tetradecanoylphorbol Acetate 116-119 ELK1, member of ETS oncogene family Mus musculus 15-20 9891065-8 1999 TPA-induced activation of the SRE was partially inhibited by dominant negative c-Raf, ERK1, or ERK2, and constitutively active mutants of PKC-alpha and PKC-epsilon activated the transactivation domain of Elk-1. Tetradecanoylphorbol Acetate 0-3 ELK1, member of ETS oncogene family Mus musculus 204-209