PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21153293-6	1996	TPA, an activator of protein kinase C, enhanced p21( ras ) and MAP-kinase activity in Nb2-11C cells but failed to induce proliferation.	Tetradecanoylphorbol Acetate	0-3	KRAS proto-oncogene, GTPase	Rattus norvegicus	48-51	
32626908-7	2020	Microglia in the group receiving 72 h of PMA stimulation displayed the highest percentage of cells arrested in G0/G1, the highest amount of senescence-associated expression of p53 and p21, and the most prominent secretion of TNF-alpha and IL-1beta.	Tetradecanoylphorbol Acetate	41-44	KRAS proto-oncogene, GTPase	Rattus norvegicus	184-187	
8663173-3	1996	Activation of PKC by 12-0-tetradecanoylphorbol-13-acetate (TPA) did not affect the basal amount of p21(ras).GTP but significantly reduced insulin-induced increases in p21(ras).GTP.	Tetradecanoylphorbol Acetate	59-62	KRAS proto-oncogene, GTPase	Rattus norvegicus	167-170	
8663173-5	1996	Depletion of PKC by an 18-h incubation with TPA or inhibition by bisindolylmaleimide resulted in profound inhibition of the insulin-induced p21(ras).GTP loading.	Tetradecanoylphorbol Acetate	44-47	KRAS proto-oncogene, GTPase	Rattus norvegicus	140-143	
26459397-9	2015	In conclusion, repeated intra-nigrostriatal treatment with PMA induced microglial senescence with increased expression levels of beta-galactosidase and p21 in the substantia nigra of the rats.	Tetradecanoylphorbol Acetate	59-62	KRAS proto-oncogene, GTPase	Rattus norvegicus	152-155	
2174364-3	1990	Down regulation of protein kinase C by prolonged exposure of hepatoma cells to TPA causes a dramatic decrease in the glucagon-stimulated effect on Ki-ras expression.	Tetradecanoylphorbol Acetate	79-82	KRAS proto-oncogene, GTPase	Rattus norvegicus	147-153	
1480166-0	1992	Transcription induction of c-Ki-ras with the tumour promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) in normal and transformed liver cells.	Tetradecanoylphorbol Acetate	61-97	KRAS proto-oncogene, GTPase	Rattus norvegicus	27-35	
1480166-0	1992	Transcription induction of c-Ki-ras with the tumour promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) in normal and transformed liver cells.	Tetradecanoylphorbol Acetate	99-102	KRAS proto-oncogene, GTPase	Rattus norvegicus	27-35	
1480166-1	1992	Results from nuclear run-off assays show that exposure of hepatocytes and Reuber H35B hepatoma cells to the tumour promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), leads to enhanced transcription of c-Ki-ras gene.	Tetradecanoylphorbol Acetate	125-161	KRAS proto-oncogene, GTPase	Rattus norvegicus	204-212	
3329719-4	1987	In contrast, in v-ras-transformed rat thyroid cells, which express very high levels of p21, treatment with either TSH, forskolin or TPA does not induce c-fos gene expression, while c-myc expression was constitutive.	Tetradecanoylphorbol Acetate	132-135	KRAS proto-oncogene, GTPase	Rattus norvegicus	87-90