PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17699780-11	2007	Overexpression of wild-type (WT) and S9A mutant GSK3beta in JB6 P+ cells suppressed EGF and TPA-mediated anchorage-independent growth in soft agar and tumorigenicity in nude mice.	Tetradecanoylphorbol Acetate	92-95	glycogen synthase kinase 3 beta	Homo sapiens	48-56	
21217772-5	2011	In Jurkat leukaemic T cells as well as in primary human T cells, tetradecanoylphorbolacetate/ionomycin- and CD3/CD28-induced RelB degradation were impaired by a GSK-3beta-specific pharmacological inhibitor, an ectopically expressed dominant-negative GSK-3beta mutant and by small-interfering RNA-mediated silencing of GSK-3beta expression.	Tetradecanoylphorbol Acetate	65-92	glycogen synthase kinase 3 beta	Homo sapiens	161-170	
21217772-5	2011	In Jurkat leukaemic T cells as well as in primary human T cells, tetradecanoylphorbolacetate/ionomycin- and CD3/CD28-induced RelB degradation were impaired by a GSK-3beta-specific pharmacological inhibitor, an ectopically expressed dominant-negative GSK-3beta mutant and by small-interfering RNA-mediated silencing of GSK-3beta expression.	Tetradecanoylphorbol Acetate	65-92	glycogen synthase kinase 3 beta	Homo sapiens	250-259	
21217772-5	2011	In Jurkat leukaemic T cells as well as in primary human T cells, tetradecanoylphorbolacetate/ionomycin- and CD3/CD28-induced RelB degradation were impaired by a GSK-3beta-specific pharmacological inhibitor, an ectopically expressed dominant-negative GSK-3beta mutant and by small-interfering RNA-mediated silencing of GSK-3beta expression.	Tetradecanoylphorbol Acetate	65-92	glycogen synthase kinase 3 beta	Homo sapiens	250-259	
24406248-7	2014	Additional differentiation inducers, phorbol 12-myristate 13-acetate and dimethyl sulfoxide, also triggered GSK-3beta-dependent apoptosis.	Tetradecanoylphorbol Acetate	37-68	glycogen synthase kinase 3 beta	Homo sapiens	108-117	
32521784-0	2020	Glycogen Synthase Kinase-3beta Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4+ T Lymphocytes.	Tetradecanoylphorbol Acetate	66-102	glycogen synthase kinase 3 beta	Homo sapiens	0-30	
27036017-3	2016	TPA dose- and time-dependently increased PKCdelta and STAT3alpha activation and GSK3beta phosphorylation; up-regulated Wnt-1, beta-catenin, and STAT3alpha expression; and increased the nuclear translocation of beta-catenin and STAT3alpha.	Tetradecanoylphorbol Acetate	0-3	glycogen synthase kinase 3 beta	Homo sapiens	80-88	
27036017-9	2016	DHA pretreatment attenuated TPA-induced cell migration, PKCdelta and STAT3alpha activation, GSK3beta phosphorylation, and Wnt-1, beta-catenin, STAT3alpha, and fascin-1 expression.	Tetradecanoylphorbol Acetate	28-31	glycogen synthase kinase 3 beta	Homo sapiens	92-100	
27036017-10	2016	Our results demonstrated that TPA-induced migration is likely associated with the PKCdelta and Wnt-1 pathways, which lead to STAT3alpha activation, GSK3beta inactivation, and beta-catenin increase and up-regulation of fascin-1 expression.	Tetradecanoylphorbol Acetate	30-33	glycogen synthase kinase 3 beta	Homo sapiens	148-156	
29271701-5	2018	Additionally, TPA-induced phosphorylations of extracellular signal-regulated kinases, 90 kDa ribosomal S6 kinase 2, c-Jun N-terminal kinases, and glycogen synthase kinase 3beta were downregulated in the presence of RGO.	Tetradecanoylphorbol Acetate	14-17	glycogen synthase kinase 3 beta	Homo sapiens	116-176	
28061416-6	2017	Furthermore, PKC activation treated with PMA could obviously up-regulate the expression of alpha-SMA and collagen I and the phosphorylation of GSK3beta, while inhibition of PKC significantly reduced GSK3beta activation.	Tetradecanoylphorbol Acetate	41-44	glycogen synthase kinase 3 beta	Homo sapiens	143-151